Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.
Showing 1-10 of 136 results
Neural Regeneration Research, 2013 • August 1, 2013
This study explored the mechanism of electroacupuncture at He-Mu points in treating visceral hypersensitivity in irritable bowel syndrome. The study demonstrated that electroacupuncture reduced P2X4 r...
KEY FINDING: Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) significantly reduced abdominal withdrawal reflex scores in rats with visceral hypersensitivity.
Neural Regen Res, 2012 • October 1, 2012
The study investigates the protective effects of pre-moxibustion at Zusanli (ST36) on gastric mucosal lesions in rats induced by absolute alcohol. It examines the role of heat shock protein 70 (HSP70)...
KEY FINDING: Pre-moxibustion at Zusanli (ST36) can protect the gastric mucosa against lesioning in rats.
Neural Regen Res, 2012 • May 1, 2012
This study aimed to verify if rat spinal cord prokineticin 1 and its receptor contribute to the analgesic effect of suspended moxibustion in a rat model of irritable bowel syndrome where rats display ...
KEY FINDING: Suspended moxibustion at Tianshu (ST25) significantly decreased visceral sensitivity to colorectal distention in rats with CVH.
Brain Sci., 2025 • February 14, 2025
Spinal cord injury (SCI) leads to secondary complications like gut dysbiosis (GD) and NLRP3 inflammasome activation, impacting mental health due to disrupted gut microbiome and inflammatory processes....
KEY FINDING: Gut dysbiosis (GD) and activation of the NLRP3 inflammasome are significant secondary complications after spinal cord injury (SCI), impacting mental health.
World Journal of Gastroenterology, 2025 • February 28, 2025
Neurosurgical patients face a high risk of stress ulcers and gastrointestinal bleeding due to factors like brain injury, spinal cord injury, and increased intracranial pressure. The review discusses b...
KEY FINDING: Stress ulcers are a significant risk for neurosurgical patients, particularly those with severe brain injuries and elevated intracranial pressure.
Frontiers in Neuroscience, 2022 • November 9, 2022
Complications after SCI significantly impact quality of life, especially gastrointestinal and bladder dysfunction. The intestinal microbiota is closely related to gastrointestinal dysfunction. After S...
KEY FINDING: SCI leads to gut dysbiosis, impacting SCFA production and associated with inflammation and infection. Gut microbiota modulates functional recovery after SCI through SCFA and the immune system. FMT may improve gastrointestinal dysfunction after SCI.
Biomedicines, 2022 • December 12, 2022
The review explores the stable gastric pentadecapeptide BPC 157's effects on striated, smooth, and heart muscles, highlighting its healing potential for myotendinous junction injuries. BPC 157 therapy...
KEY FINDING: BPC 157 therapy shows potential in healing severed myotendinous junctions, combining healing of transected and detached tendons, muscles, ligaments, and bones.
J Vet Intern Med, 2023 • March 1, 2023
This study evaluated the efficacy of prophylactic omeprazole in preventing gastrointestinal (GI) complications in dogs undergoing surgery for acute thoracolumbar intervertebral disc extrusion (TL-IVDE...
KEY FINDING: The frequency of GI signs was not significantly different between the omeprazole and placebo groups (P = .59).
Scientific Reports, 2023 • April 3, 2023
This study investigated the impact of chronic gut dysbiosis induced by E. coli on the progression of ALS in a mouse model. The researchers found that introducing curli-producing E. coli shifted the gu...
KEY FINDING: Chronic gut exposure to curli-producing E. coli led to significant shifts in the diversity of gut bacteria in male hSOD1 mice.
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology), 2023 • April 1, 2023
This study explores the therapeutic potential of short-chain fatty acids (SCFAs) in spinal cord injury (SCI) recovery by modulating the gut microbiome and immune response. Oral administration of SCFAs...
KEY FINDING: Oral administration of SCFAs improved locomotor function in SCI rats, as indicated by increased BBB scores, improved regularity index, and decreased base of support (BOS) value.