Neural Regen Res, 2012 · DOI: 10.3969/j.issn.1673-5374.2012.15.004 · Published: May 1, 2012
This study investigates the effect of suspended moxibustion on chronic visceral hypersensitivity (CVH) in rats, a model for irritable bowel syndrome. The researchers focused on prokineticin 1 (PK1) and its receptor (PKR1) in the spinal cord, as these are involved in pain signaling. The findings suggest that suspended moxibustion can reduce visceral sensitivity and decrease the expression of PK1 and PKR1 in the spinal cord, potentially alleviating pain associated with irritable bowel syndrome.
PK1 and PKR1 could be potential therapeutic targets for managing visceral pain in conditions like IBS.
The study provides insights into the mechanisms by which moxibustion may alleviate visceral hypersensitivity.
Suspended moxibustion may be a beneficial alternative treatment for patients with irritable bowel syndrome.