Critical Care Research

KEY FINDING: Droxidopa was successfully used to manage hypotension in two patients with acute SCI who experienced bradycardia with midodrine.

KEY FINDING: 79.2% of patients successfully weaned off IV vasopressors after the addition of midodrine.

KEY FINDING: Early decompressive surgery within 24 hours post-injury is widely supported for patients with spinal instability or cord compression, enhancing motor recovery, especially in incomplete SCI.

KEY FINDING: Prophylactic iNPPV was associated with a lower incidence of pneumonia compared to usual care in patients with acute CSCIs.

KEY FINDING: Early intensive care unit (ICU) monitoring improves patient prognosis, highlighting the importance of prompt ICU admission and early decompression surgery.

KEY FINDING: Early decompression (within 24 hours) may improve neurological outcomes, but the evidence is not definitive and may be influenced by study methodology and patient heterogeneity.

KEY FINDING: Stress ulcers are a significant risk for neurosurgical patients, particularly those with severe brain injuries and elevated intracranial pressure.

KEY FINDING: The mean age of patients with ATSCI above T6 increased significantly over the 20-year period (49 vs. 51 vs. 57 years; P = 0.046), as did their Charlson Comorbidity Index (CCI).

KEY FINDING: Ultrasound evaluation revealed diaphragmatic dysfunction in a patient with C3 spinal cord injury.

KEY FINDING: The study found that systemic vascular resistance index (SVRI) was significantly reduced compared to normal ranges in non-SCI patients, regardless of vasopressor use.