Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.
Showing 131-136 of 136 results
Journal of Nanobiotechnology, 2025 • February 11, 2025
The intestinal microbiome plays an important role in SCI and regulating intestinal microbiome promotes SCI repair. Pectin-Zein-IPA NPs treatment improves motor function recovery, inhibits the activati...
KEY FINDING: Pec-Zein-IPA NPs treatment improves motor function recovery and activates AKT/Nrf-2 signaling pathway following SCI.
Neural Regeneration Research, 2016 • June 1, 2016
This study investigates the central neuromechanisms underlying the control of intragastric pressure through acupuncture at Zusanli (ST36) in rats, with a focus on the upper cervical cord's role. The f...
KEY FINDING: Zusanli acupuncture effectively elevated intragastric pressure, even after complete dorsal cord transection.
The Journal of Spinal Cord Medicine, 2020 • January 1, 2020
This study introduces a novel nerve transfer technique to restore anorectal function in rats after spinal cord injury (SCI). The procedure involves creating an artificial reflex arc by anastomosing L5...
KEY FINDING: The study found that the new nerve pathway connecting the spine to the anorectal muscles was successfully established in rats with SCI.
BMC Gastroenterology, 2018 • September 3, 2018
This study evaluates the use of vedolizumab in Austrian pediatric patients with IBD who had previously failed TNF-α antagonist treatment. The results suggest that vedolizumab can be an effective treat...
KEY FINDING: In the UC group, complete clinical remission was achieved at weeks 2, 6, and 14 in 2/5, 1/5 and 1/5 patients respectively; partial response was observed in one patient at week 2.
BioMed Research International, 2019 • June 2, 2019
The study investigates the therapeutic potential of nAG protein in a rat model of liver fibrosis induced by carbon tetrachloride (CCL4). Results showed that nAG treatment significantly reduced serum l...
KEY FINDING: CCL4 treatment significantly increased serum levels of hyaluronic acid, PDGF-AB, TIMP-1, laminin, procollagen III N-terminal peptide, and collagen IV-alpha 1 chain.
Exp Neurol, 2020 • January 1, 2020
This review addresses how SCI changes the physiological interplay between the spinal cord, the gut and the immune system. A suspected culprit in causing many of the pathological manifestations of impa...
KEY FINDING: SCI leads to gut dysbiosis, characterized by changes in the composition and abundance of gut bacteria, such as a decrease in Bacteroidales and an increase in Clostridiales.