Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.
Showing 21-30 of 136 results
Journal of Neuroinflammation, 2021 • May 7, 2021
The study aimed to elucidate the system-wide changes induced by minocycline treatment in a rodent model of cervical SCI, focusing on the microbiota-immune axis and behavioral outcomes. Minocycline tre...
KEY FINDING: Minocycline had a profound acute effect on the microbiota diversity and composition, which was paralleled by the subsequent normalization of spinal cord injury-induced suppression of cytokines/chemokines.
PLoS ONE, 2024 • October 21, 2024
This nationwide cross-sectional study in the Netherlands investigated the prevalence of bladder and bowel problems among individuals with multiple sclerosis (MS) and their referral pathways to various...
KEY FINDING: 91% of respondents experienced bladder problems, and 73% had bowel problems.
Journal of Orthopaedic Surgery and Research, 2023 • June 22, 2023
This study investigated the impact of neurogenic bowel dysfunction (NBD) on the quality of life (QoL) in Chinese individuals with spinal cord injury (SCI). It highlights the management strategies used...
KEY FINDING: Prolonged defecation time (>60 minutes) significantly deteriorates the quality of life in SCI patients.
The Journal of Spinal Cord Medicine, 2024 • January 1, 2024
This study evaluated the efficacy of the Peristeen Anal Irrigation System (PAIS) in people with Cauda Equina Syndrome (CES) experiencing neurogenic bowel dysfunction. Participants used the PAIS bowel ...
KEY FINDING: The Neurogenic Bowel Dysfunction (NBD) score significantly improved after the 10-week intervention with the PAIS system.
The Journal of Spinal Cord Medicine, 2023 • May 1, 2023
The study aimed to evaluate the relationship between the severity of neurogenic bowel dysfunction (NBD) and functional status, depression, and quality of life (QoL) in individuals with spinal cord inj...
KEY FINDING: Half of the individuals with SCI in the study had moderate-to-severe NBD.
The Journal of Spinal Cord Medicine, 2023 • January 1, 2023
This case study investigates the use of electrical rectal stimulation (ERS) as an alternative to digital rectal stimulation (DRS) for bowel management in an individual with a spinal cord injury. The r...
KEY FINDING: ERS was associated with effective bowel emptying in the participant.
Medicina, 2023 • July 19, 2023
This case report describes a 77-year-old woman with cauda equina syndrome (CES) who developed a stercoral ulcer after undergoing extensive spinal fusion surgery. The patient's condition was complicate...
KEY FINDING: A 77-year-old woman with CES developed a stercoral ulcer in the sigmoid colon after undergoing extensive posterior lumbar interbody fusion.
Med Sci Monit, 2023 • October 25, 2023
This study evaluated the efficacy of quantitative assessment-based nursing interventions on bowel function recovery, quality of life, and caregivers’ satisfaction with SCI patients with NBD. At 6 mont...
KEY FINDING: Patients receiving quantitative assessment-based nursing interventions showed significant reductions in fecal incontinence, constipation, and abdominal distension compared to those receiving no nursing intervention.
Frontiers in Human Neuroscience, 2023 • October 12, 2023
This scoping review examined the evidence on neurogenic bowel dysfunction (NBD) following acquired brain injury (ABI) and identified ten relevant studies. The review highlights the complex interplay b...
KEY FINDING: The incidence of fecal incontinence ranges from 41 to 68% during admission to rehabilitation, dropping to 12–36% at discharge, and reaching 5% 1 year after discharge.
J. Clin. Med., 2023 • November 7, 2023
Neurogenic bowel dysfunction is a complex and common condition among patients with SCI and MS. It is highly burdensome due to constipation, fecal incontinence, abdominal bloating, and pain. The aim of...
KEY FINDING: The existing treatment pyramid includes experimental treatments and treatments not available at all centers, making it misaligned with clinical practice.