Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 471-480 of 12,052 results
Journal of Cellular and Molecular Medicine, 2024 • November 26, 2024
This study investigated the protective effects of quercetin, a compound found in the Chinese herbal formula Jisuikang (JSK), on spinal cord injury (SCI). The research used network pharmacology to iden...
KEY FINDING: Quercetin, a key ingredient in Jisuikang (JSK), protects microglial cells from LPS-induced inhibition of cell viability and cellular inflammation.
BMC Musculoskeletal Disorders, 2025 • November 26, 2024
This retrospective study assessed the effectiveness of intraoperative electrophysiological monitoring in detecting postoperative neurological deficits in scoliotic patients undergoing surgical correct...
KEY FINDING: Intraoperative monitoring was used in approximately 60% of scoliosis surgeries with reported complications.
J Yeungnam Med Sci, 2025 • November 26, 2024
This case report describes a patient who developed focal hand dystonia due to hemorrhage of a cervical spinal mass, a previously unreported cause. The patient underwent surgery to excise the mass, fol...
KEY FINDING: The patient presented with right upper extremity weakness, numbness, and pain radiating from the neck, along with an abnormal posture in the right hand.
Advanced Science, 2025 • November 25, 2024
This study introduces a novel COCu-Tac-iNSCs transplantation system to address challenges in cell-based therapies for spinal cord injury, such as graft rejection and mitochondrial dysfunction. The sel...
KEY FINDING: The COCu-Tac hydrogel promotes the survival and neuronal differentiation of transplanted iNSCs without systemic immunosuppression, leading to improved outcomes compared to iNSCs alone.
Scientific Reports, 2024 • November 25, 2024
This study examined the potential of GnRH and GH treatments to promote neurotrophic and synaptic recovery in ovariectomized rats with thoracic SCI. The results showed that chronic administration of Gn...
KEY FINDING: GnRH and GH treatments upregulate the expression of neurotrophic and synaptogenic activity genes in rats with SCI.
Cellular and Molecular Neurobiology, 2025 • November 25, 2024
This review comprehensively examines the therapeutic potential of exosomal miRNAs in treating various central nervous system injury diseases. It covers traumatic brain injury, ischemic stroke, intrace...
KEY FINDING: Exo-miR-124 facilitates M2 polarization of microglia through the inhibition of the TLR4 pathway, thereby affecting hippocampal neurogenesis and the recovery of neurological behavior and cognition after TBI.
Journal of Pain Research, 2024 • November 25, 2024
This study used the Experience Sampling Method (ESM) to investigate the relationship between pain intensity, physical activity, and psychosocial factors in patients with Small Fiber Neuropathy (SFN). ...
KEY FINDING: More pain now can result in more physical activity later, influenced by pain catastrophic thoughts and fatigue.
J. Clin. Med., 2024 • November 25, 2024
This study uses artificial neural networks to predict rehabilitation outcomes in spinal cord injury patients, focusing on the impact of psychological variables. The model considers clinical and demogr...
KEY FINDING: Psychological factors accounted for 36.3% of the total predictive weight for functional outcomes in SCI patients.
Interventional Pain Medicine, 2024 • November 25, 2024
This review summarizes the interventional pain management methods used for pediatric CRPS, noting the lack of high-quality evidence and specific protocols for diagnosis and management. Techniques like...
KEY FINDING: Interventional pain management methods like continuous epidural anesthesia, lumbar sympathetic blocks, and spinal cord stimulation have been used safely and successfully in treating pediatric CRPS as part of a multimodal strategy.
Journal of Nanobiotechnology, 2024 • November 24, 2024
This review discusses the role of dynamic spatiotemporal inflammation in secondary injuries after SCI, elaborates on the mechanism of action and effect of existing nanomaterials in treating SCI, and s...
KEY FINDING: Spatiotemporal dynamic neuroinflammation plays an important role in secondary injury after SCI. Inflammatory cells and mediators have different roles at different stages of inflammation.