Latest Research Summaries

KEY FINDING: EJCDs promote HSC self-renewal and erythroid differentiation in the bone marrow by upregulating FZD4 protein expression in LSK cells.

KEY FINDING: The disruption of the blood-spinal cord barrier after injury leads to an imbalance in the immunological microenvironment, triggering neuroinflammation.

KEY FINDING: Following SCI, reduced ReHo values were observed in the left primary somatosensory cortex, left striatum, right agranular insular cortex, and partial cortex in the limbic system, which was reversed after HBOT.

KEY FINDING: The patient presented with a T12 schwannoma accompanied by an intratumoral hematoma, experiencing sudden and unbearable pain in the lower limbs.

KEY FINDING: Parents/caregivers of younger children (8–12 years) with SCI prioritized “bladder” function, “leg/foot movement”, and “bowel” function.

KEY FINDING: Mitochondrial transplantation (MT) reduces neuronal death and promotes axonal regeneration after spinal cord injury by regulating the MAPK/ERK and PI3K/Akt signaling pathways.

KEY FINDING: Both interventions demonstrated a time effect on CS (P = 0.001) with interaction between both groups (P = 0.01).

KEY FINDING: The translation and cross-cultural adaptation process led to clarifications and definitions being added to the original questions to suit the Nepali context.

KEY FINDING: Participants with sarcopenic obesity had significantly lower FIM motor scores than those without the condition (54 vs. 69 points, p = 0.006).

KEY FINDING: Dorsal Root Ganglion (DRG) stimulation and Spinal Cord Stimulation (SCS) demonstrated statistically significant pain reduction.