Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 461-470 of 12,052 results
Journal of Exercise Rehabilitation, 2024 • December 1, 2024
This study compared the effects of weight-bearing (treadmill) and non-weight-bearing (swimming) exercise on recovery after spinal cord injury (SCI) in rats. It assessed motor function, corticospinal t...
KEY FINDING: Motor function, as measured by the BBB score, improved significantly more in the swimming group compared to the sedentary group at 3 and 6 weeks after SCI.
Neurochemical Research, 2025 • November 30, 2024
The study developed a novel slow-release nanoparticle estrogen (SNP-E2) delivery system that provides sustained release of E2 in the injured spinal cord without systemic exposure. Delivery of E2 via S...
KEY FINDING: SNP-E2 delivery reduced inflammation and gliosis, and induced microglial differentiation of M1 to M2 in rats after SCI.
Cureus, 2024 • November 30, 2024
This study investigated factors linked to mortality and morbidity in pediatric head and spinal injuries to determine effective treatment strategies. The study analyzed 303 patients, predominantly male...
KEY FINDING: Road traffic accidents (RTA) at 147 (48.5%) and falls at 139 (45.9%) were the most common traumas.
Front. Neurosci., 2024 • November 29, 2024
This editorial highlights recent advancements and diverse applications of brain-computer interfaces (BCIs) in managing neurological disorders, aiming to enhance quality of life and functional abilitie...
KEY FINDING: Combining epidural electrical stimulation (EES) with near-infrared nerve stimulation (nINS) can enhance motor function specificity in spinal cord injury (SCI) rats by selectively activating target muscles.
Cellular and Molecular Neurobiology, 2024 • November 28, 2024
Neuropathic pain after SCI is caused by glial cells, ectopic firing of neurons endings and their intra- and extracellular signaling mechanisms. SCI causes activation of astrocytes and microglia across...
KEY FINDING: Activated astrocytes and microglia are essential for the development and maintenance of SCI-NP.
Heliyon, 2024 • November 28, 2024
This study investigates the therapeutic potential of Tanshinone IIA (Tan IIA) in treating spinal cord injury induced by fluoride exposure in rats. The findings indicate that fluoride exposure leads to...
KEY FINDING: Fluoride exposure induces spinal cord injury with aberrant biomarkers, including increased mRNA levels of Mmp9, TNF-α, IL-1β, Mag, P53, NF-κB, and GSK3β, and decreased mRNA levels of Mbp.
Brain and Spine, 2024 • November 28, 2024
This narrative review consolidates knowledge on the acute phase management of tSCI patients within the context of polytrauma, underscoring the necessity of a multidisciplinary approach. It highlights ...
KEY FINDING: Damage control resuscitation (DCR) and damage control surgery (DCS) are essential for preventing and correcting post-traumatic physiological derangements to minimize bleeding until hemostasis is achieved.
Healthcare, 2024 • November 28, 2024
The review examines the experience of implementing SCI transitional care in Hong Kong, focusing on the service model, facilitators, barriers, and future development. Service output and outcomes were e...
KEY FINDING: SCI transitional care in Hong Kong offers person-centred support including residential rehabilitation, community day rehabilitation, and residential respite care.
J. Clin. Med., 2024 • November 27, 2024
Individuals with SCI experience a pattern of decline during aging that is different from individuals without SCI. Muscle atrophy and skeletal muscle fiber type transformation occur rapidly and in uniq...
KEY FINDING: Muscle atrophy after SCI involves a rapid shift to type II fast-twitch glycolytic fibers, unlike the typical loss of type II fibers in normal aging. This leads to significant strength and endurance reduction.
Spinal Cord Series and Cases, 2024 • November 27, 2024
This project aimed to compare the incidence of TBI at the NSIC to figures found in previous research and to understand the barriers to identifying and considering TBI during rehabilitation at the NSIC....
KEY FINDING: Data related to TBI were inconsistently recorded, and the number of individuals recorded as having a TBI at the center was lower than a recent study.