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  4. Interventional pain management of CRPS in the pediatric population: A literature review

Interventional pain management of CRPS in the pediatric population: A literature review

Interventional Pain Medicine, 2024 · DOI: https://doi.org/10.1016/j.inpm.2024.100532 · Published: November 25, 2024

Pain ManagementPediatrics

Simple Explanation

This review explores the use of interventional pain management techniques for children with Complex Regional Pain Syndrome (CRPS). These techniques, like nerve blocks and spinal cord stimulation, aim to reduce pain and improve function when other treatments haven't worked. The review found that while these interventions can be helpful, the evidence is limited, mostly based on case reports. More research is needed to establish clear guidelines for diagnosing and treating pediatric CRPS with these methods. Interventional procedures were typically implemented after failed conservative management (92.89%), which included multiple medications (e.g., pregabalin, amitriptyline, NSAIDs) combined with physical and psychological therapy.

Study Duration
From January 1st, 2000 to April 2nd, 2024
Participants
183 patients aged 7–18 years, with female predominance (81.4%)
Evidence Level
Predominantly case reports (70%) and case series (19%)

Key Findings

  • 1
    Interventional pain management methods like continuous epidural anesthesia, lumbar sympathetic blocks, and spinal cord stimulation have been used safely and successfully in treating pediatric CRPS as part of a multimodal strategy.
  • 2
    Most studies evaluated the success of the intervention based on pain scale improvement, physical capability, or engagement in activities.
  • 3
    A notable finding of 15.30% of pediatric CRPS cases presented with a spontaneous onset, a proportion that is markedly higher than typically observed in adult populations.

Research Summary

This review summarizes the interventional pain management methods used for pediatric CRPS, noting the lack of high-quality evidence and specific protocols for diagnosis and management. Techniques like continuous epidural anesthesia, lumbar sympathetic blocks, peripheral procedures, and spinal cord stimulation have been safely and successfully used as part of a multimodal treatment strategy. The review emphasizes the need for further research to establish clear guidelines for CRPS diagnosis and management in pediatric patients.

Practical Implications

Need for Standardized Protocols

The lack of standardized diagnostic and treatment protocols highlights the need for developing specific guidelines for pediatric CRPS.

Further Research

More high-quality research is required to determine the efficacy and long-term outcomes of interventional pain management techniques in children with CRPS.

Multimodal Approach

Interventional techniques should be integrated into a comprehensive, multimodal treatment strategy that includes physical and psychological therapy.

Study Limitations

  • 1
    The studies included provide low-quality evidence, consisting mainly of case reports and case series.
  • 2
    There is a lack of consensus regarding diagnostic criteria, treatment protocols, and assessment methods.
  • 3
    The data search was limited to English publications, potentially overlooking relevant literature.

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