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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 341-350 of 12,052 results

Spinal Cord InjuryPain ManagementPublic Health

The influence of pain on community reintegration after spinal cord injury

Pain Practice, 2025 • January 1, 2025

This study investigated the influence of pain on community reintegration among manual wheelchair users with spinal cord injury (SCI). It examined the associations between neuropathic pain, nociceptive...

KEY FINDING: Most participants (85.2%) reported current pain, with neuropathic pain (53.3%) being more common than nociceptive shoulder pain (14.8%).

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NeurologyNeurorehabilitation

Preserved force control by the digits via minimal sparing of cortico-spinal connectivity after stroke

Experimental Physiology, 2025 • January 1, 2025

This case report examines cortico-spinal connectivity required for force control by the digits after neurological injury. The study documents a stroke survivor capable of controlling finger forces dur...

KEY FINDING: A stroke survivor retained the ability to control finger forces at a level comparable to neurologically intact adults despite extensive white matter loss.

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Spinal Cord InjuryNeurologyRehabilitation

Exercise therapy facilitates neural remodeling and functional recovery post-spinal cord injury via PKA/CREB signaling pathway modulation in rats

Burns & Trauma, 2025 • January 1, 2025

The study found that exercise therapy (ET) enhances the PKA/CREB signaling pathway in neurons after spinal cord injury (SCI). ET significantly improved hindlimb motor function and promoted the formati...

KEY FINDING: Exercise therapy (ET) counteracts the H89-induced suppression of the PKA/CREB signaling pathway following spinal cord injury (SCI).

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Spinal Cord InjuryUrologyMental Health

Effects of a self-efficacy-centered self-management program on neurogenic bladder after spinal cord injury: A randomized controlled trial

Japan Journal of Nursing Science, 2025 • January 1, 2025

This research aimed to investigate the effects of a self-efficacy-centered self-management program on persons with neurogenic bladder (NGB) after spinal cord injury (SCI). The self-efficacy-centered s...

KEY FINDING: The intervention group demonstrated significantly better outcomes than the control group at 12 weeks post-intervention in self-management ability.

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Spinal Cord InjuryPharmacologyBiomedical

A cryo‑shocked M2 macrophages based treatment strategy promoting repair of spinal cord injury via immunomodulation and axonal regeneration effects

Journal of Nanobiotechnology, 2025 • January 1, 2025

The study presents LNT M2/PTX-NPs@Gel as an effective treatment for SCI, demonstrating significant improvements in neurological function recovery. The treatment modulates the inflammatory microenviron...

KEY FINDING: LNT M2/PTX-NPs@Gel treatment significantly improved motor function recovery in SCI rats, as evidenced by increased BBB scores and MEP amplitudes.

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Spinal Cord InjuryAlternative MedicineRehabilitation

Efficacy analysis of acupuncture and rehabilitation for traumatic spinal cord injury

Medicine, 2025 • January 1, 2025

This study investigates the role and efficacy of acupuncture combined with rehabilitation therapy during the recovery phase of patients with traumatic spinal cord injury. Posttreatment assessments rev...

KEY FINDING: Acupuncture combined with rehabilitation therapy led to significant improvements in residual urine volume and detrusor pressure compared to rehabilitation therapy alone.

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Spinal Cord InjuryNeurologyRehabilitation

Short- and long-­term effects of transcutaneous spinal cord stimulation on autonomic cardiovascular control and arm-­crank exercise capacity in individuals with a spinal cord injury (STIMEX-­SCI): study protocol

BMJ Open, 2025 • January 1, 2025

This study aims to determine the effects of transcutaneous spinal cord stimulation (TSCS) on cardiovascular control and exercise capacity in individuals with spinal cord injury (SCI). The study will i...

KEY FINDING: The study will examine whether TSCS improves volitional upper-body exercise capacity in the short- and long-term.

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Spinal Cord InjuryAssistive TechnologyRehabilitation

Correction: A Fully Immersive Virtual Reality Method for Upper Limb Rehabilitation in Spinal Cord Injury

Ann Rehabil Med, 2025 • January 1, 2025

This is a corrigendum to a previously published article in the Annals of Rehabilitation Medicine. The correction addresses a missing acknowledgment for funding received from Chungnam National Universi...

KEY FINDING: The original article omitted an acknowledgment of funding from Chungnam National University Hospital Research Fund, 2019.

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Spinal Cord InjuryNeurologyGenetics

Resveratrol Upregulates miR-124-3p Expression to Target DAPK1, Regulating the NLRP3/Caspase-1/GSDMD Pathway to Inhibit Pyroptosis and Alleviate Spinal Cord Injury

Journal of Cellular and Molecular Medicine, 2025 • January 1, 2025

This study investigates the potential therapeutic role of resveratrol (RES) and miR-124-3p in mitigating pyroptosis and promoting recovery from spinal cord injury (SCI). The research demonstrates that...

KEY FINDING: DAPK1 interacts with NLRP3, promoting pyroptosis via the NLRP3/Caspase-1/GSDMD pathway. Knocking down DAPK1 inhibits pyroptosis.

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UrologyNeurologyRehabilitation

Clinical efficacy of bladder function training combined with pelvic floor biofeedback electrical stimulation on neurogenic bladder and its impact on urodynamics

Pak J Med Sci, 2025 • January 1, 2025

This study evaluated the clinical efficacy of bladder function training combined with pelvic floor biofeedback electrical stimulation in treating neurogenic bladder after spinal cord injury. The study...

KEY FINDING: Bladder function training combined with pelvic floor biofeedback electrical stimulation showed a significantly higher response rate compared to conventional treatment and bladder function training alone (82% vs 62%).

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