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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 351-360 of 12,052 results

Spinal Cord InjuryNeurologyPain Management

Improved Motor Function in Cervical Spinal Cord Injury Following Spinal Cord Stimulation

Clinical Case Reports, 2025 • January 1, 2025

This case report presents a 60-year-old male with a cervical spinal cord injury (SCI) who experienced significant improvements in motor function, spasticity, and pain after receiving spinal cord stimu...

KEY FINDING: The patient experienced a 60% improvement in spasticity and a 50% improvement in mobility of his right upper extremity following SCS.

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Spinal Cord InjuryMental Health

Association Between Traumatic Spinal Cord Injury and Psychiatric Disorders, Mental Illness and Dementia: A Systematic Review and Meta-Analysis

Global Spine Journal, 2025 • January 1, 2025

This study assessed the correlation between TSCI patients and anxiety, The results of meta-analysis showed that the risk of anxiety in TSCI patients was significantly higher than that in control group,...

KEY FINDING: Patients with traumatic spinal cord injury were at significantly higher risk of anxiety, depression, psychosis, dementia, insomnia, adjustment disorders, mood disorders, personality disorders, alcohol-related disorders, substance-use disorders, adjustment reactions, drug dependence, and central pain relative to patients with non-traumatic spinal cord injury (P < 0.05).

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EndocrinologyRehabilitation

A Home‐Based Behaviour Change Intervention With Sedentary Behaviour and Physical Activity in People With Stroke and Diabetes—A Feasibility and Safety Study

Physiotherapy Research International, 2025 • January 1, 2025

This study aimed to determine the feasibility and safety of the ELiR intervention in stroke survivors with DM targeting SB and PA through motivational interviewing. Overall, the intervention was feasi...

KEY FINDING: The ELiR intervention showed high adherence among participants.

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Spinal Cord InjuryHealthcareTrauma

Management of traumatic spinal cord injury in the Nordic countries: a multidisciplinary survey

Scand J Trauma Resusc Emerg Med, 2025 • January 1, 2025

This study surveyed current practices in the Nordic countries for managing traumatic spinal cord injuries (TSCI), covering pre-hospital, intensive care, surgery, and rehabilitation stages. The survey ...

KEY FINDING: Preoperative magnetic resonance imaging (MRI) was available to most spine surgeons on a 24/7 basis and considered mandatory prior to surgery by the majority.

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Spinal Cord InjuryRehabilitationPublic Health

A Community Reintegration Model for Persons With Traumatic Spinal Cord Injury in South Africa: Process and Outcomes

Advances in Rehabilitation Science and Practice, 2025 • January 1, 2025

The study developed a multidimensional model to improve community reintegration (CR) for individuals with traumatic spinal cord injuries (TSCI) in South Africa, addressing a significant gap between po...

KEY FINDING: The study revealed low levels of psychosocial and community reintegration among individuals with TSCI in South Africa, significantly influenced by employment and housing factors.

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Spinal Cord InjuryNeurologyGenetics

Intranasal Delivery of Brain-Derived Neurotrophic Factor (BDNF)-Loaded Small Extracellular Vesicles for Treating Acute Spinal Cord Injury in Rats and Monkeys

Journal of Extracellular Vesicles, 2025 • January 1, 2025

The study investigates the therapeutic potential of intranasally administered BDNF-loaded small extracellular vesicles (BDNF-sEVs) for acute spinal cord injury (SCI) in rats and monkeys. Results demon...

KEY FINDING: BDNF loading enhances the neurite outgrowth promoted by sEVs in cultured neurons, suggesting an improved neurotrophic effect.

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NeurologyGenetics

Secretome of the Olfactory Ensheathing Cells Influences the Behavior of Neural Stem Cells

Int. J. Mol. Sci., 2024 • December 31, 2024

This study characterized the protein content of the human olfactory ensheathing cell (OEC) secretome and investigated its effects on neural stem cells (NSCs). The secretome was found to contain 709 pr...

KEY FINDING: The study identified 709 proteins in the human OEC secretome from three donors. Thirty-nine proteins, including neurological-related proteins (profilin-1) and antioxidants (peroxiredoxin-1 and glutathione S-transferase), were shared between the six samples.

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UrologyNeurology

Implantable Neuromodulation for Neurogenic Lower Urinary Tract Dysfunction: A Single-Institution Retrospective Study

International Neurourology Journal, 2024 • December 31, 2024

This retrospective study investigates the effectiveness of implantable neuromodulation for patients with neurogenic lower urinary tract dysfunction (NLUTD) at a single institution from 2008 to 2020. T...

KEY FINDING: Neuromodulation, both sacral and pudendal, is a feasible and effective treatment option for NLUTD, with a significant percentage of patients experiencing symptom improvement.

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SurgeryMedical ImagingOrthopedics

Delayed Neurological Deficits Following Lumbar 1 Burst Fracture: A Diagnostic Challenge Without Radiological Correlates

Cureus, 2024 • December 31, 2024

This case report presents a diagnostic challenge involving a patient with a stable L1 burst fracture who developed delayed neurological deficits without corresponding radiological abnormalities. The p...

KEY FINDING: A 55-year-old man with a stable L1 burst fracture developed delayed neurological deficits two weeks after sustaining a fall, despite no evidence of intrinsic or extrinsic spinal cord abnormalities on MRI.

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Alternative MedicineNeurologyResearch Methodology & Design

Sciatic nerve injury treated by acupuncture: a bibliometric study and visualization analysis

Frontiers in Neurology, 2024 • December 31, 2024

This study uses visualization software VOSviewer and CiteSpace to provide the current status and trends in SNI of acupuncture over the past decade and predicts potential research frontiers and hot dir...

KEY FINDING: Acupuncture combined with drug therapy, physical therapy, and rehabilitation training can comprehensively improve the treatment effect for sciatic nerve injury.

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