Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 331-340 of 12,052 results
CNS Neuroscience & Therapeutics, 2025 • January 1, 2025
This study investigates the role of Vof16 in nociceptive sensation induced by SNI, revealing that disrupting Vof16 elevates the excitability of neurons but does not independently drive hyperalgesia in...
KEY FINDING: SNI led to the downregulation of Vof16 expression in spinal dorsal horn (SDH) of lumbar enlargement.
International Journal of Particle Therapy, 2025 • January 1, 2025
This study compares proton SBRT to photon SBRT for spinal metastases, using variable RBE dose models to assess the impact on target coverage and sparing of organs at risk. The results suggest that IMP...
KEY FINDING: Proton therapy (IMPT) significantly improved planning target volume coverage compared to photon therapy (PH-SBRT) at both 30 Gy and 45 Gy doses.
Proteins: Structure, Function, and Bioinformatics, 2025 • January 1, 2025
This study demonstrates that valacyclovir and acyclovir, commonly used antiviral drugs, are substrates of the enzyme cypin, which deaminates these compounds. The research uses NADH-coupled assays, try...
KEY FINDING: Valacyclovir and acyclovir are deaminated by cypin, meaning cypin breaks them down.
Medicine, 2025 • January 1, 2025
This clinical case report assesses the outcomes of postural drainage targeting the intervertebral space, combined with chemotherapy, for treating thoracolumbar tuberculosis. Eight cases of thoracolum...
KEY FINDING: Postural drainage focusing on the intervertebral space, combined with chemotherapy, led to significant improvements in erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Visual Analogue Scale (VAS) score, American Spinal Cord Injury Association (ASIA) score, and Oswestry functional index.
Journal of Orthopaedic Case Reports, 2025 • January 1, 2025
This retrospective case series investigated the use of low-cost negative pressure dressing (NPD) in managing sacral pressure injuries (PIs) in five patients, alongside an individualized rehabilitation...
KEY FINDING: The study found a 42.86% average improvement in Functional Independence Measure (FIM) scores from admission to discharge, indicating improved functional outcomes.
The Journal of Spinal Cord Medicine, 2025 • January 1, 2025
This study confirmed the responsiveness of the Trunk Assessment Scale for Spinal Cord Injury (TASS) and estimated the minimal clinically important difference (MCID) for the TASS. The findings suggest ...
KEY FINDING: The changes in the TASS and those in the other assessments were weakly correlated at 1 month and moderately correlated at discharge.
The Journal of Spinal Cord Medicine, 2025 • January 1, 2025
The bibliometric analysis shows a rapid increase in SRMA applications in SCI research. The study identifies key methodological concerns among a randomly selected set of articles. The authors provide g...
KEY FINDING: The use of SRMA in SCI research has increased rapidly since 2009, with an annual growth rate of approximately 15%.
The Journal of Spinal Cord Medicine, 2025 • January 1, 2025
This study investigated the effects of a weight support feedback walker (WSFW) on walker dependence, lower limb muscle activation, and gait ability in patients with incomplete spinal cord injury (ISCI...
KEY FINDING: The WSFW group showed a significant decrease in walker dependence compared to the CW group.
The Journal of Spinal Cord Medicine, 2025 • January 1, 2025
This study evaluated the short-term impact of nerve transfer (NT) and tendon transfer (TT) surgeries on upper extremity function in individuals with cervical spinal cord injury (SCI), compared to a no...
KEY FINDING: The TT group had a decline in SCIM and SF-36 scores whereas the NT and no surgery groups experienced little change in independence or health status in the immediate perioperative period.
Australian Occupational Therapy Journal, 2025 • January 1, 2025
This scoping review examined manual wheelchair (MWC) training approaches and intended outcomes for adults new to wheelchair use. The review found that training often focuses on skill acquisition and c...
KEY FINDING: Manual wheelchair training programs often target individuals with spinal cord injuries, potentially overlooking the needs of older adults or those with progressive conditions.