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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Research Methodology & Design Research

Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.

Showing 51-60 of 702 results

UrologyGeneticsResearch Methodology & Design

Xanthogranulomatous epididymo‑orchitis: A single‑institutional case series and systematic review

Indian Journal of Urology, 2023 • December 29, 2022

This study presents a case series and systematic review of xanthogranulomatous epididymo-orchitis (XGEO), a rare inflammatory condition affecting the male genital organs. The research analyzes clinica...

KEY FINDING: XGEO often presents as a subacute or chronic condition, predominantly affecting men in their 50s and 60s. Symptoms include swelling, tenderness, or pain in the scrotal region.

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OncologyMedical ImagingResearch Methodology & Design

Carotid body paraganglioma metastatic to spine causing cord compression: a case report

Diagnostic Pathology, 2023 • February 10, 2023

This case report describes a rare presentation of carotid body paraganglioma (CBT) with distant metastasis to the thoracic spine, resulting in spinal cord compression in a 40-year-old female. The pati...

KEY FINDING: Carotid body tumors, while typically benign, can exhibit metastatic potential, even many years after initial diagnosis and treatment.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

Clinical Trials Targeting Secondary Damage after Traumatic Spinal Cord Injury

Int. J. Mol. Sci., 2023 • February 14, 2023

This review summarizes clinical trials focused on mitigating secondary damage after traumatic spinal cord injury (SCI). It categorizes therapeutic strategies into early procedural interventions, pharm...

KEY FINDING: Early decompression surgery (within 24 hours of injury) is associated with better neurological recovery in thoracic or thoracolumbar SCI patients.

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Spinal Cord InjuryGeneticsResearch Methodology & Design

Mapping the landscape A bibliometric perspective on autophagy in spinal cord injury

Medicine, 2024 • July 12, 2024

This bibliometric study provides a comprehensive overview of research trends, hotspots, and key contributors in the field of autophagy and spinal cord injury (SCI). The analysis identifies influential...

KEY FINDING: The number of publications related to autophagy and SCI has generally increased from 2009 to 2023, peaking in 2020.

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Spinal Cord InjuryNeurologyResearch Methodology & Design

Post-traumatic cauda equina nerve calcification: A case report

World Journal of Clinical Cases, 2023 • February 26, 2023

This case report presents a rare instance of post-traumatic cauda equina nerve calcification in a 52-year-old patient with a history of lumbar spinal stenosis and vertebral fracture. The patient exhib...

KEY FINDING: The patient presented with weakness in hip flexion, knee extension, and plantarflexion in the right lower limb, with muscle strength grade 3.

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NeurologyResearch Methodology & DesignBiomechanics

Gait analysis in swine, sheep, and goats after neurologic injury: a literature review

Neural Regeneration Research, 2023 • September 1, 2023

Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials. This review focuses on swine, sheep, and goats...

KEY FINDING: Swine and sheep were well-suited for a variety of assessment designs, with treadmill walking and guided free walking offering the most consistency across multiple trials.

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Spinal Cord InjurySurgeryResearch Methodology & Design

Early versus late surgical intervention for cervical spinal cord injury A protocol for systematic review and meta-analysis

Medicine, 2023 • March 1, 2023

This systematic review and meta-analysis protocol aims to compare the efficacy of early versus late surgical intervention for acute cervical spinal cord injury (SCI). The study will search multiple da...

KEY FINDING: The primary outcome will be the change in the American Spinal Injury Association score from baseline to follow-up.

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Spinal Cord InjuryResearch Methodology & DesignMusculoskeletal Medicine

Prognosis and conditional nomogram of cervical spine fracture in patients with severe spinal cord injury: a multicenter retrospective study

International Journal of Surgery, 2023 • March 31, 2023

The study aimed to evaluate the instantaneous death risk and conditional survival (CS) of patients with cervical spine fractures and severe SCI, and developed conditional nomograms to predict survival...

KEY FINDING: The instantaneous death risk was highest during the first 12 months after injury.

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Spinal Cord InjuryOrthopedicsResearch Methodology & Design

Acute Paraparesis in a Patient after High Velocity Manipulation of Cervical Spine and its Management

Journal of Orthopaedic Case Reports, 2022 • November 1, 2022

This case report highlights a rare instance of acute paraparesis following cervical spine manipulation performed by a non-registered person, emphasizing the potential risks associated with such proced...

KEY FINDING: A 57-year-old male developed paraparesis following a neck manipulation by a non-registered person (barber).

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SurgerySpinal DisordersResearch Methodology & Design

Aggressive thoracic vertebral hemangioma: case report and literature review

Spinal Cord Series and Cases, 2023 • May 11, 2023

This case report describes a rare instance of an aggressive thoracic vertebral hemangioma in a 39-year-old female, leading to paraplegia and pain. The patient was successfully treated with a combinati...

KEY FINDING: Aggressive vertebral hemangiomas can cause significant pain and neurological symptoms due to spinal cord compression.

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