Browse the latest research summaries in the field of biomechanics for spinal cord injury patients and caregivers.
Showing 1-10 of 209 results
Biomech Model Mechanobiol, 2012 • January 1, 2012
This study examined the impact of mechanical strain and TGF-β1 on urinary bladder wall smooth muscle remodeling using an ex vivo organ culture system. Results showed that a 0.5-Hz strain induced elast...
KEY FINDING: A 0.5-Hz strain frequency triangular waveform stimulation at 15% strain resulted in fibrillar elastin production, collagen turnover, and a more compliant ECM.
JOR Spine, 2024 • October 10, 2024
This study uses finite element analysis to compare different hybrid revision surgery strategies for two-level discontinuous adjacent segment degeneration (ASD) following anterior cervical discectomy a...
KEY FINDING: The D-C-D model, which uses artificial discs at both adjacent levels, showed the most significant reduction in biomechanical stress compared to other revision surgery models.
bioRxiv preprint, 2025 • February 28, 2025
This article introduces the Neuromusculoskeletal Modeling (NMSM) Pipeline, a MATLAB-based software package that provides researchers and clinicians working together with state-of-the-art computational...
KEY FINDING: The software predicted that the subject could increase his walking speed by 60% without increasing his metabolic cost per unit time by modifying existing muscle synergy recruitment.
Archives of Orthopaedic and Trauma Surgery, 2023 • July 5, 2022
This study evaluated the resistance of different cup/liner systems to lever-out forces, a potential cause of liner dissociation in THA. The Pinnacle system with intact ARTs showed the highest stabilit...
KEY FINDING: The Pinnacle construct with intact ARTs required the greatest force to achieve dissociation, followed by Plasmafit Plus7 and Allofit-S constructs.
Spinal Cord, 2023 • August 23, 2022
This study aimed to assess the construct validity and test-retest reliability of the 2mWT in individuals with SCI. The main findings of the present study are that in individuals with SCI (1) the walkin...
KEY FINDING: The 2mWT is highly correlated with the 6mWT, indicating it measures similar aspects of walking function.
Medicine, 2022 • October 14, 2022
The study uses finite element analysis to simulate indirect reduction of thoracolumbar burst fractures with posterior pedicle screw fixation, focusing on the mechanics of vertebral body restoration an...
KEY FINDING: Extension (positional reduction) helps restore the normal height and kyphosis of the injured vertebrae, concentrating stress on the upper disc.
BMC Musculoskeletal Disorders, 2022 • December 1, 2022
The study investigates the biomechanical effects of spinal shortening using finite element analysis to determine the optimal shortening distance during surgery. The results suggest that increasing spi...
KEY FINDING: Increasing spinal shortening distance generally increased stress on internal rods and the range of motion and intradiscal pressure of adjacent segments.
Front. Bioeng. Biotechnol., 2024 • July 2, 2024
This study investigates the biomechanical changes in the spinal cord during scoliosis correction surgery using patient-specific finite element models. The aim is to understand the mechanisms of spinal...
KEY FINDING: Stress concentration in the spinal cord was observed in patients with poor prognosis, aligning with their clinical manifestations of neurological dysfunction. For example, patient a showed stress concentration at the T8-T9 segments, consistent with paraplegia at that level.
Heliyon, 2023 • February 3, 2023
This study investigates the relationship between gluteal muscle shear modulus and intramuscular stress/strain using a semi-3D finite element model of the human buttock to understand deep tissue injury...
KEY FINDING: Increased gluteal muscle stiffness, represented by a higher shear modulus, leads to increased compressive stress, strain energy density, and average von Mises stress within the muscle.
Neural Regeneration Research, 2023 • September 1, 2023
Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials. This review focuses on swine, sheep, and goats...
KEY FINDING: Swine and sheep were well-suited for a variety of assessment designs, with treadmill walking and guided free walking offering the most consistency across multiple trials.