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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Biomechanics Research

Browse the latest research summaries in the field of biomechanics for spinal cord injury patients and caregivers.

Showing 1-10 of 209 results

UrologyCardiovascular ScienceBiomechanics

Strain history and TGF-β1 induce urinary bladder wall smooth muscle remodeling and elastogenesis

Biomech Model Mechanobiol, 2012 • January 1, 2012

This study examined the impact of mechanical strain and TGF-β1 on urinary bladder wall smooth muscle remodeling using an ex vivo organ culture system. Results showed that a 0.5-Hz strain induced elast...

KEY FINDING: A 0.5-Hz strain frequency triangular waveform stimulation at 15% strain resulted in fibrillar elastin production, collagen turnover, and a more compliant ECM.

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SurgeryBiomechanics

Finite element analysis of two-level discontinuous cervical hybrid revision surgery strategy to reduce biomechanical responses of adjacent segments

JOR Spine, 2024 • October 10, 2024

This study uses finite element analysis to compare different hybrid revision surgery strategies for two-level discontinuous adjacent segment degeneration (ASD) following anterior cervical discectomy a...

KEY FINDING: The D-C-D model, which uses artificial discs at both adjacent levels, showed the most significant reduction in biomechanical stress compared to other revision surgery models.

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RehabilitationBiomechanics

The Neuromusculoskeletal Modeling Pipeline: MATLAB-based Model Personalization and Treatment Optimization Functionality for OpenSim

bioRxiv preprint, 2025 • February 28, 2025

This article introduces the Neuromusculoskeletal Modeling (NMSM) Pipeline, a MATLAB-based software package that provides researchers and clinicians working together with state-of-the-art computational...

KEY FINDING: The software predicted that the subject could increase his walking speed by 60% without increasing his metabolic cost per unit time by modifying existing muscle synergy recruitment.

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OrthopedicsBiomechanics

Dissociation of liner from cup in THA: does liner damage affect the risk of dissociation?

Archives of Orthopaedic and Trauma Surgery, 2023 • July 5, 2022

This study evaluated the resistance of different cup/liner systems to lever-out forces, a potential cause of liner dissociation in THA. The Pinnacle system with intact ARTs showed the highest stabilit...

KEY FINDING: The Pinnacle construct with intact ARTs required the greatest force to achieve dissociation, followed by Plasmafit Plus7 and Allofit-S constructs.

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Spinal Cord InjuryRehabilitationBiomechanics

Validity and reliability of the 2-minute walk test in individuals with spinal cord injury

Spinal Cord, 2023 • August 23, 2022

This study aimed to assess the construct validity and test-retest reliability of the 2mWT in individuals with SCI. The main findings of the present study are that in individuals with SCI (1) the walkin...

KEY FINDING: The 2mWT is highly correlated with the 6mWT, indicating it measures similar aspects of walking function.

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SurgeryOrthopedicsBiomechanics

Finite element analysis of the indirect reduction of posterior pedicle screw fixation for a thoracolumbar burst fracture

Medicine, 2022 • October 14, 2022

The study uses finite element analysis to simulate indirect reduction of thoracolumbar burst fractures with posterior pedicle screw fixation, focusing on the mechanics of vertebral body restoration an...

KEY FINDING: Extension (positional reduction) helps restore the normal height and kyphosis of the injured vertebrae, concentrating stress on the upper disc.

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SurgeryBiomechanics

Biomechanical comparison of spinal column shortening ‑ a finite element study

BMC Musculoskeletal Disorders, 2022 • December 1, 2022

The study investigates the biomechanical effects of spinal shortening using finite element analysis to determine the optimal shortening distance during surgery. The results suggest that increasing spi...

KEY FINDING: Increasing spinal shortening distance generally increased stress on internal rods and the range of motion and intradiscal pressure of adjacent segments.

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Spinal Cord InjuryOrthopedicsBiomechanics

Biomechanical analysis of spinal cord injury during scoliosis correction surgery

Front. Bioeng. Biotechnol., 2024 • July 2, 2024

This study investigates the biomechanical changes in the spinal cord during scoliosis correction surgery using patient-specific finite element models. The aim is to understand the mechanisms of spinal...

KEY FINDING: Stress concentration in the spinal cord was observed in patients with poor prognosis, aligning with their clinical manifestations of neurological dysfunction. For example, patient a showed stress concentration at the T8-T9 segments, consistent with paraplegia at that level.

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Spinal Cord InjuryDermatologyBiomechanics

Stiffening of the gluteal muscle increased the intramuscular stress: An in-silico implication of deep tissue injury

Heliyon, 2023 • February 3, 2023

This study investigates the relationship between gluteal muscle shear modulus and intramuscular stress/strain using a semi-3D finite element model of the human buttock to understand deep tissue injury...

KEY FINDING: Increased gluteal muscle stiffness, represented by a higher shear modulus, leads to increased compressive stress, strain energy density, and average von Mises stress within the muscle.

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NeurologyResearch Methodology & DesignBiomechanics

Gait analysis in swine, sheep, and goats after neurologic injury: a literature review

Neural Regeneration Research, 2023 • September 1, 2023

Medical research on neurologic ailments requires representative animal models to validate treatments before they are translated to human clinical trials. This review focuses on swine, sheep, and goats...

KEY FINDING: Swine and sheep were well-suited for a variety of assessment designs, with treadmill walking and guided free walking offering the most consistency across multiple trials.

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