Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 1-10 of 200 results
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2013 • January 1, 2013
This case report describes the successful treatment of a small intramedullary schwannoma using minimally invasive hemilaminectomy. The patient experienced symptom improvement and no tumor recurrence d...
KEY FINDING: Intramedullary schwannomas can be successfully removed via minimally invasive hemilaminectomy, preserving spinal stability.
PLoS ONE, 2013 • September 10, 2013
This study identifies SOCS1 as a novel target gene of the Hh/GLI signaling pathway in epidermal and neural tumor cells. The Hh/GLI pathway, when activated, upregulates SOCS1 expression. Upregulation o...
KEY FINDING: SOCS1 is identified as a direct transcriptional target of Hh/GLI signaling in human keratinocytes and medulloblastoma cells.
Neural Regen Res, 2013 • June 1, 2013
This study investigated the effects of X-irradiation on glial scar formation and functional recovery in rats with spinal cord injury. The researchers aimed to determine the optimal time window for X-i...
KEY FINDING: X-irradiation at 8 Gy reduced the expression of macrophage marker ED-1, indicating a decrease in inflammation.
Journal of Cancer, 2014 • September 20, 2014
This review discusses the role of fibroblasts in salamander limb regeneration and contrasts their activity with that of human fibroblasts in wound healing and cancer. It examines how the salamander's ...
KEY FINDING: Salamander regeneration can reverse tumorigenicity, as demonstrated by the reversion of frog tumor cells to normal tissues in regenerating limbs.
Global Spine Journal, 2025 • January 1, 2023
This retrospective cohort study compared neurological outcomes and retreatment rates in multiple myeloma patients with high-grade ESCC treated with radiotherapy or surgery. The study found that surgic...
KEY FINDING: Surgical treatment was associated with significantly lower odds for neurological deterioration compared to radiotherapy (OR = .15; 95% CI .05 - .44; P < .01).
Strahlentherapie und Onkologie, 2024 • August 29, 2024
The study evaluates the feasibility and toxicity of robustly optimized intensity-modulated proton therapy (IMPT) in treating skull base chordoma and chondrosarcoma. The results indicate that IMPT is a...
KEY FINDING: Robustly optimized IMPT is clinically feasible as a postoperative treatment for skull base chordoma and chondrosarcoma patients.
Journal of Medical Case Reports, 2024 • November 23, 2024
This case report describes a rare instance of spinal schwannoma presenting with intraspinal hematoma in a 53-year-old female. The patient experienced sudden lower limb pain, necessitating emergency su...
KEY FINDING: The patient presented with a T12 schwannoma accompanied by an intratumoral hematoma, experiencing sudden and unbearable pain in the lower limbs.
Cureus, 2025 • January 16, 2025
This case highlights the vast diversity of pediatric spinal tumors and their potential for favorable postoperative outcomes. It also provides evidence for the existence of benign, fibrolipomatous infl...
KEY FINDING: The patient had an extensive extradural, intracanal mass from T1 to T10 causing spinal cord compression.
Acta Neurochirurgica, 2025 • January 19, 2025
This study retrospectively reviewed data from 72 patients who underwent surgery for spinal schwannomas to identify factors associated with residual neurological deficits. The study found that thoracic...
KEY FINDING: Thoracic spine involvement is a significant risk factor for residual neurological deficits after surgery (OR, 5.03; 95% CI, 1.47–18.6; p = 0.01).
Biomedicines, 2025 • February 12, 2025
This study investigates the effects of Ganoderic Acid DM (GA-DM), a natural extract from Ganoderma lucidum, on B-cell lymphoma. The research demonstrates that GA-DM exhibits anti-proliferative activit...
KEY FINDING: GA-DM induces apoptosis in human B-cell lymphoma cell lines DB and Toledo, and orchestrates autophagy and apoptosis in the murine B-cell lymphoma cell line A20.