Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 71-80 of 200 results
Medicina, 2024 • April 13, 2024
This meta-analysis evaluated the outcomes of different surgery timings for acute symptomatic MSCC, focusing on emergent (≤24 h), urgent (≤48 h), and late (>48 h) surgeries. The study found that urgent...
KEY FINDING: Urgent decompression (within 48 hours of symptom onset) leads to significantly better neurological outcomes for patients with a life expectancy of over three months.
Cancers, 2024 • April 25, 2024
This study evaluated the impact of concurrent cytopathology (CP) analysis alongside histopathology (HP) on the time to diagnosis (TTD) and time to therapy (TTT) in patients undergoing spinal surgery f...
KEY FINDING: The mean time to diagnosis (TTD) with cytopathology (CP) was significantly shorter (1.7 days) compared to histopathology (HP) (8.4 days).
GMJ, 2023 • October 23, 2023
The role of miRNAs in BC metastasis to the brain represents a potential treatment approach. Hence, by investigating the complex networks of miRNA-based molecular alterations and their potential role a...
KEY FINDING: MiR-10b has been identified as a metastasis-promoting miRNA, influencing tumor invasiveness and enhancing colonization of BC cells to the brain by targeting various genes involved in cell adhesion and angiogenesis
BMC Urology, 2024 • April 1, 2024
This systematic review highlights the increased risk of bladder cancer in patients with spinal cord injury (SCI), addressing both clinical characteristics and underlying molecular mechanisms. The revi...
KEY FINDING: The incidence and mortality rates of bladder cancer are higher in spinal cord injury (SCI) patients compared to the general population.
Frontiers in Pharmacology, 2024 • May 20, 2024
This case report presents a patient with advanced HCC and spinal cord compression who was treated with a combination of QL1604 and bevacizumab, resulting in improved motor function, tumor shrinkage, a...
KEY FINDING: The patient's paralysis symptoms gradually improved, and the motor function of the lower limbs completely returned to normal after treatment with QL1604 and bevacizumab.
Int. J. Mol. Sci., 2024 • May 24, 2024
This study investigates the neuropathological consequences of extracranial radiation therapy (ECRT) in mice, focusing on the brain and spinal cord changes following radiation exposure to the hindlimb....
KEY FINDING: ECRT induces dose-dependent changes in gene and protein expression in the brain, affecting neurotransmission, glial cell activation, and immune signaling.
Cancer Reports, 2024 • July 1, 2024
This study investigates secretome biomarkers in glioblastoma cancer stem cells using bioinformatics analysis to identify potential therapeutic targets and prognostic markers. The research identifies d...
KEY FINDING: The study identified 890 differentially expressed genes (DEGs) in GBM cells, with 475 upregulated and 415 downregulated.
Advanced Science, 2023 • March 12, 2023
This review discusses the role of bacteria in tumorigenesis, the latest advances in bacteria-based delivery platforms, and the existing obstacles for application. The review summarizes the application...
KEY FINDING: Certain types of tumor have their own unique microbial composition, which has an important role in the survival of cancer patients.
Frontiers in Endocrinology, 2023 • September 1, 2023
This study developed a nomogram to predict postoperative HRQoL in lung cancer patients with MSCC, using ECOG score, targeted therapy, anxiety score, and number of comorbidities as predictors. The nomo...
KEY FINDING: Four key variables were identified for predicting HRQoL: ECOG score, targeted therapy, anxiety scale, and number of comorbidities.
International Journal of Surgery Case Reports, 2023 • April 24, 2023
This case report describes a rare complication of TACE, spinal cord ischemia, in a patient with HCC. The patient experienced paraplegia and sensory deficits following the procedure. The etiology is hy...
KEY FINDING: A 78-year-old male with chronic hepatitis B and HCC developed acute paraplegia and sensory loss after a second TACE procedure.