Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 61-70 of 200 results
Neurosurgical Review, 2023 • November 21, 2023
This study compares surgical outcomes in elderly patients (65–79 years vs. ≥ 80 years) undergoing laminectomy for spinal metastasis with epidural spinal cord compression (MESCC). The research found th...
KEY FINDING: Octogenarians had significantly higher age-adjusted Charlson Comorbidity Index (CCI) scores compared to the 65–79 age group, indicating a greater burden of comorbidities.
J BONE ONCOL, 2023 • October 30, 2023
This study establishes and characterizes an immunocompetent mouse model of prostate cancer-induced bone pain (PCa-CIBP) by injecting RM1-GFP cells into the femur of C57BL/6 mice. The model exhibits os...
KEY FINDING: Intra-femoral injection of RM1 prostate cancer cells in mice led to a progressive increase in hindlimb guarding, indicating spontaneous pain.
Spine, 2024 • March 1, 2024
The study developed a deep learning-based AI model for detecting osteolytic bone metastases in the thoracolumbar spine using CT scans. The AI model demonstrated comparable sensitivity to experts and i...
KEY FINDING: The AI model achieved a sensitivity of 0.78, precision of 0.68, and F1-score of 0.72 per slice in detecting osteolytic bone metastases.
Cancer Medicine, 2024 • January 1, 2024
This retrospective study analyzed data from 11,380 admissions for metastatic prostate cancer with spinal cord compression, comparing treatment approaches and outcomes between teaching and non-teaching...
KEY FINDING: A greater percentage of patients underwent surgical intervention at TH compared to NTH.
Frontiers in Oncology, 2023 • December 12, 2023
This study evaluated the efficacy and safety of 3D-printed tissue compensations in breast cancer patients receiving breast reconstruction and postmastectomy radiotherapy (PMRT). The 3D-printed bolus e...
KEY FINDING: The 3D-printed bolus ensures the dose coverage of the planning target volume (PTV) with a homogeneity index (HI) of 0.12.
Japanese Journal of Radiology, 2024 • February 28, 2024
This retrospective study evaluated the efficacy and safety of re-irradiation SBRT for metastatic epidural spinal cord compression (MESCC) following high-dose conventional radiotherapy. The study found...
KEY FINDING: Re-irradiation spine SBRT may be effective for selected patients with cervical or thoracic MESCC, even with high-dose irradiation histories.
Scientific Reports, 2024 • January 19, 2024
This study utilized a quantitative technique to compare pre- and postoperative CT artifacts produced by CF and titanium implants in patients with spinal oligometastatic disease (OMD) undergoing stereo...
KEY FINDING: Significant increases in Hounsfield units (HU) were observed at the vertebral body, pedicle, and spinal cord at the lowest instrumented vertebra level for both carbon-fiber (CF) and titanium implants.
British Journal of Cancer, 2024 • April 11, 2024
This study provides a comprehensive single-cell landscape of human chordoma and highlights its heterogeneity and the role played by TGF-β in chordoma progression. The findings substantiate the potenti...
KEY FINDING: Single-cell transcriptome sequencing identified VEGFR and TGF-β as therapeutic targets in chordoma.
Scientific Reports, 2024 • April 8, 2024
In this study, we employed enhanced division time attribute extraction and max- and min-rationalizing techniques for image analysis. Specifically, we applied these methods to identify glioblastoma, a ...
KEY FINDING: The accuracy of the proposed TAE-PIS system is 98.12% which is higher when compared to other methods like Genetic algorithm, Convolution neural network, fuzzy-based minimum and maximum neural network and kernel-based support vector machine respectively.
Orthopaedic Surgery, 2024 • June 1, 2024
This study compared the outcomes of patients with spinal metastases and pathological fractures treated with either decompression and pedicle screw fixation (fixation group) or microwave ablation combi...
KEY FINDING: The MWA group exhibited reduced blood loss compared to the fixation group (p = 0.01).