Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.
Showing 81-90 of 200 results
Pain Research and Management, 2022 • July 8, 2022
This study explored the relationship between pain, bone metastasis, and cytokine expression in cancer patients treated with external radiation therapy. The research aimed to identify specific cytokine...
KEY FINDING: Radiotherapy significantly improved pain scores and quality of life in cancer patients with bone metastasis.
The Journal of Spinal Cord Medicine, 2024 • January 1, 2024
This retrospective study analyzed data from 40 patients with Metastatic Spinal Cord Compression (MSCC) admitted to a specialist spinal cord injury rehabilitation center between 2013 and 2021. The stud...
KEY FINDING: Patients with MSCC showed a significant improvement in Spinal Cord Independence Measure (SCIM) scores after a six-week inpatient rehabilitation program.
Asian Spine Journal, 2023 • April 1, 2023
The study evaluated postoperative functional status using FIM-L, WISCI II, ASIA-LEMS, and ASIA-LESS scores, finding that independent walkers at 2 weeks had better lower-limb and sensory function recov...
KEY FINDING: 71% and 43% of participants were nonindependent ambulators at 1 week and 2 weeks postoperatively, respectively.
Clin Case Rep, 2023 • June 26, 2023
This case report describes a 79-year-old man who presented with tetraplegia secondary to spinal cord compression caused by multiple myeloma affecting the T1 vertebra. The patient underwent surgical de...
KEY FINDING: The patient presented with acute-onset paraplegia secondary to spinal cord compression from a T1 vertebral lesion caused by multiple myeloma.
Frontiers in Endocrinology, 2023 • July 26, 2023
The editorial discusses how bone homeostasis affects tumor bone metastasis, highlighting that bone metastasis is a common complication of malignant tumors, influenced by interactions in the bone micro...
KEY FINDING: Dysregulation of bone remodeling impairs immune cell function, leading to immune evasion and promoting tumor cell survival and growth in the bone.
Am J Phys Med Rehabil, 2024 • March 1, 2024
Spinal tumors, whether primary or metastatic, pose significant risks of debilitating complications; however, timely and comprehensive care can lead to improved patient outcomes. A multidisciplinary ap...
KEY FINDING: Multidisciplinary approach involving physiatrists is effective in managing spinal tumors and mitigating complications.
Cureus, 2024 • April 23, 2024
This case report describes the physiotherapy rehabilitation of a 40-year-old male with grade II ependymomas and spinal cord compression, focusing on improving functional recovery and quality of life. ...
KEY FINDING: The patient's motor score in the lower extremity improved from 0/50 to 20/50 on the ASIA Impairment Scale after physiotherapy rehabilitation.
Medicina, 2024 • May 27, 2024
This study aimed to identify factors associated with the discharge destination of patients with bone metastases, finding that spinal cord compression (SCC), hypercalcemia, and functional ambulation ca...
KEY FINDING: Spinal cord compression (SCC) was significantly associated with discharge to a non-home setting (OR 3.37, 95% CI 1.35–8.43).
CANCER BIOLOGY & THERAPY, 2024 • December 3, 2024
This study investigates the efficacy of dinaciclib, a Cdk inhibitor, in treating biliary tract cancer (BTC) using in vitro models. The findings indicate that dinaciclib reduces cell viability, ATP lev...
KEY FINDING: Dinaciclib reduces cell viability, ATP levels, and proliferation rates in BTC cells.
The Journal of Spinal Cord Medicine, 2022 • March 1, 2022
The study compared demographic data, injury characteristics, medical comorbidities, and functional outcomes of neoplastic and traumatic SCI patients in an inpatient rehabilitation program. Neoplastic ...
KEY FINDING: Neoplastic SCI patients were significantly older than traumatic SCI patients.