Immunology Research

KEY FINDING: The study will evaluate if 6 weeks of antibiotics is non-inferior to 12 weeks for infections with retained implants.

KEY FINDING: Hippocampal damage in NMOSD can result from direct astrocyte injury and subsequent microglial activation and neuronal damage within the hippocampus.

KEY FINDING: TPPU restored mechanical and thermal thresholds in rats treated with nab-paclitaxel, indicating pain relief.

KEY FINDING: EP injuries significantly increased SubP, Iba1, and GFAP in the dorsal horn of the spinal cord, indicating spinal cord sensitization and neuroinflammation.

KEY FINDING: Pharmacological inhibition of sTNF in the spinal cord after T9-SCI restores anti-viral immunity in mice challenged with live influenza.

KEY FINDING: The patient presented with an unusual combination of persistent flaccid weakness and areflexia alongside tract-specific myelopathy, a novel presentation for neurosyphilis.

KEY FINDING: Endogenous B cells play a significant beneficial role in the regulation of neuroinflammation following acute injury to the central nervous system

KEY FINDING: The Col/Tac hydrogel exhibited suitable mechanical properties and long-term sustained Tac release behaviour.

KEY FINDING: Acupuncture alleviates neuroinflammation by inhibiting the activation of the NLRP3 inflammasome pathway, thereby improving the progression of CNS diseases.

KEY FINDING: SCI leads to primary physical injury followed by secondary injury caused by inflammation, ischemia, oxidative stress, axonal degeneration and glial scar formation.