Immunology Research

KEY FINDING: One-stage tracheostomy during surgery significantly reduced the development of pneumonia at 7 days after tracheostomy compared to necessary tracheostomy after surgery.

KEY FINDING: Oral administration of SCFAs improved locomotor function in SCI rats, as indicated by increased BBB scores, improved regularity index, and decreased base of support (BOS) value.

KEY FINDING: MHC class I and II reporter mice enable reliable detection of immune oligodendroglia in the CNS.

KEY FINDING: 3% GelMA-A was identified as the optimal hydrogel formulation due to its mechanical properties and cytocompatibility.

KEY FINDING: Treg cells can repair the spinal cord by affecting the polarization of macrophages/microglia, shifting them from a pro-inflammatory (M1) to a neuroprotective (M2) phenotype.

KEY FINDING: The 60-year-old female patient developed bilateral upper extremity tremors, high fever, and confusion, leading to a diagnosis of West Nile encephalitis.

KEY FINDING: Knockdown of spastin inhibits HIV-1 Gag protein production and new virion formation by enhancing Gag lysosomal degradation.

KEY FINDING: The patient met the diagnostic criteria for AQP4-IgG positive NMOSD with undifferentiated connective tissue disease and multiple peripheral neuropathy.

KEY FINDING: BSCB disruption occurs rapidly after SCI and spreads to adjacent spinal segments, with gaps appearing in the tight junctions of small vessels.

KEY FINDING: Candida albicans was identified as the causative agent of spondylodiscitis in this patient, highlighting the importance of considering fungal etiologies in such infections.