Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 4,051-4,060 of 12,052 results
BRAIN, 2022 • September 5, 2022
The study investigates spinal cord associative plasticity (SCAP) as a method to enhance sensorimotor function after cervical spinal cord injury in rats. Results showed that SCAP, involving timed pairi...
KEY FINDING: Subthreshold spinal cord stimulation significantly enhanced motor cortex evoked muscle potentials when paired synchronously in the spinal cord, demonstrating the importance of timing.
Frontiers in Pharmacology, 2022 • September 5, 2022
This review summarizes the neuroprotective effects of TMP on various CNS diseases, including ICVD, SCI, PD, AD, CI, MI, and depression. The protective effects of TMP against these CNS diseases are bas...
KEY FINDING: TMP exhibits neuroprotective effects against ischemic cerebrovascular diseases by inhibiting calcium overload, glutamate excitotoxicity, oxidative stress, inflammation, and apoptosis, while also protecting the blood-brain barrier and enhancing synaptic plasticity.
BMC Urology, 2022 • September 5, 2022
This scoping review examined the impact of hydrophilic versus non-hydrophilic intermittent catheters on various outcomes in patients with urinary retention. The review included 77 articles and found t...
KEY FINDING: HCICs generally lead to greater UTI reduction and improved satisfaction, cost-effectiveness, and quality of life.
Cells, 2022 • September 5, 2022
This study investigates the therapeutic potential of human induced pluripotent stem cell-derived neural progenitor cells (iPSC-NPCs) for treating cervical spinal cord injury (SCI) in rats. The key fin...
KEY FINDING: iPSC-NPCs were able to survive and differentiate into both neurons and astrocytes after transplantation into a cervical contusion SCI rat model.
Scientific Reports, 2022 • September 5, 2022
The study investigates cervical spine injuries in older adults, highlighting falls as the primary cause, particularly falls from ground level. Clinical characteristics and outcomes differ based on the...
KEY FINDING: Ground-level falls are the most common cause of cervical spine injuries in older adults.
Contemporary Clinical Trials Communications, 2022 • September 3, 2022
This qualitative study investigated the experiences of patients participating in the PAPAartis clinical trial, which aims to prevent spinal cord injuries during thoracoabdominal aortic aneurysm repair...
KEY FINDING: Patients participate in clinical trials due to trust in doctors, hope for better treatment, and altruistic motives, but often struggle to understand the complex information provided.
Cureus, 2022 • September 3, 2022
This case report describes the successful use of mechanical insufflation-exsufflation (MIE) therapy in a 67-year-old cervical spinal cord injury (SCI) patient with lung infection and atelectasis who w...
KEY FINDING: MIE therapy led to improvement of atelectasis (collapsed lung) in a cervical SCI patient within one day of starting treatment.
Materials Today Bio, 2022 • September 2, 2022
The review summarizes the progress made in the applications of GSNO in anti-infective biomaterials. It mainly includes the biological properties of GSNO and its application in biomaterials and provid...
KEY FINDING: GSNO possesses antibacterial activity influenced by factors like bacterial strain, dose, treatment duration, and NO release kinetics. Studies have evaluated GSNO's antibacterial properties in pulmonary, cutaneous, and other infections.
Nature Communications, 2022 • September 2, 2022
This study examined the impact of biological sex mismatch on neural progenitor cell (NPC) transplantation outcomes in a mouse model of spinal cord injury (SCI). The research found that male NPC grafts...
KEY FINDING: The biological sex of donor cells does not significantly influence graft neuron density, glial differentiation, formation of the reactive glial cell border, or graft axon outgrowth.
Cellular & Molecular Biology Letters, 2022 • September 2, 2022
This study investigates the evolutionary dynamics and function of progranulins (PGRNs) in lampreys, primitive vertebrates known for their regenerative abilities. Four genes encoding PGRNs were identif...
KEY FINDING: Four PGRN genes were identified in lampreys: one long form (Lr-PGRN-L) and three short forms (Lr-PGRN-S1, Lr-PGRN-S2, and Lr-PGRN-S3).