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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 391-400 of 12,052 results

ImmunologyOrthopedicsResearch Methodology & Design

Cervical spine infection arising from chronic paronychia: A case report and review of literature

World Journal of Orthopedics, 2024 • December 18, 2024

This case report presents a unique instance of a 15-year-old male developing acute cervical spine pyogenic infection (CSPI) secondary to chronic paronychia caused by Staphylococcus aureus. The patient...

KEY FINDING: The study highlights a rare case of cervical spine pyogenic infection (CSPI) stemming from chronic paronychia, emphasizing that infections can originate from unexpected sources.

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Cardiovascular SciencePhysiologyMedical Imaging

Posterior Cerebral Circulation Insufficiency Due to Internal Carotid Artery Stenosis With an Atypical Vertebral Artery Originating From the Internal Carotid Artery Territory

Cureus, 2024 • December 18, 2024

The case report highlights a rare anatomical variation where the vertebral artery originates from the internal carotid artery, potentially leading to posterior circulation neurological deficits if the...

KEY FINDING: A dominant right vertebral artery was found to originate from the right internal carotid artery in a 76-year-old female.

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Cardiovascular ScienceEducation

Simulator training in focus assessed transthoracic echocardiography (FATE) for undergraduate medical students: results from the FateSim randomized controlled trial

BMC Medical Education, 2025 • December 18, 2024

This study compares the effectiveness of simulator-based ultrasound training to traditional ultrasound training with human subjects for teaching theoretical and practical skills in Focused Assessed Tr...

KEY FINDING: Both simulator- and human-based training effectively developed theoretical and practical skills in FATE.

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Spinal Cord InjuryRegenerative Medicine

Long-term clinical and safety outcomes from a single-site phase 1 study of neural stem cell transplantation for chronic thoracic spinal cord injury

Cell Reports Medicine, 2024 • December 17, 2024

This study reports the long-term results for a phase 1 study of neural stem cell transplantation for chronic spinal cord injury. Here, we report that all four subjects tolerated the stem cell implanta...

KEY FINDING: All four subjects tolerated the stem cell implantation procedure well, with no serious adverse events immediately following the procedure.

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Spinal Cord InjuryEndocrinologyMusculoskeletal Medicine

A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury

Cell Reports Medicine, 2024 • December 17, 2024

This study investigates why severe injury to the central nervous system (CNS) triggers the development of large neurogenic heterotopic ossifications (NHOs) within periarticular muscles. The central rol...

KEY FINDING: Severe SCI causes a spike in blood corticosterone in mice, which is causal for NHO development.

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EndocrinologyOrthopedicsRehabilitation

Osteoporosis Knowledge and Awareness Among Patients and Accompanying Attendants: A Cross-Sectional Study in a Physical Medicine and Rehabilitation Department

Cureus, 2024 • December 17, 2024

This cross-sectional study assessed osteoporosis knowledge among 300 patients and attendants at a Physical Medicine and Rehabilitation department using the OKAT-H questionnaire. The study revealed a s...

KEY FINDING: The mean OKAT-H score was found to be 9.82 out of 20 (49.1%) with a standard deviation of 5.06.

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Spinal Cord InjuryUrology

Impact of bladder management methods and other factors on sexual activity in women with chronic spinal cord injury/disease

Sexual Medicine, 2024 • December 17, 2024

The study aimed to investigate the effect of bladder evacuation method on sexual activity in women with chronic SCI/D. Around half of the evaluated women were sexually active, regardless of bladder ev...

KEY FINDING: Significantly more women using intermittent catheterization (IC) were sexually active compared to those with a suprapubic catheter (SPC).

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Spinal Cord InjuryRegenerative MedicineGenetics

Mesenchymal Stem Cells and Their Extracellular Vesicles: Therapeutic Mechanisms for Blood–Spinal Cord Barrier Repair Following Spinal Cord Injury

Int. J. Mol. Sci., 2024 • December 16, 2024

Spinal cord injury (SCI) disrupts the blood–spinal cord barrier (BSCB) exacerbating damage by allowing harmful substances and immune cells to infiltrate spinal neural tissues from the vasculature. Mes...

KEY FINDING: MSCs and MSC-EVs reduce BSCB permeability after SCI, promoting vascular stability and functional recovery in preclinical models.

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Spinal Cord InjuryRegenerative MedicineBiomedical

Co-culturing neural and bone mesenchymal stem cells in photosensitive hydrogel enhances spinal cord injury repair

Front. Bioeng. Biotechnol., 2024 • December 16, 2024

This study investigates the use of co-cultured neural stem cells (NSCs) and bone mesenchymal stem cells (BMSCs) within a low-modulus GelMA hydrogel scaffold to enhance spinal cord injury (SCI) repair....

KEY FINDING: Low-modulus GelMA hydrogels promote cell migration, viability, and proliferation of co-cultured NSCs and BMSCs in vitro.

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PharmacologyImmunologyNeurology

Humanized anti-CD11d monoclonal antibodies suitable for basic research and therapeutic applications

Antibody Therapeutics, 2025 • December 16, 2024

This research describes the creation and characterization of humanized anti-CD11d monoclonal antibodies as potential therapeutics for inflammatory conditions. In vitro and in vivo studies demonstrated...

KEY FINDING: The researchers successfully developed and characterized five humanized anti-CD11d monoclonal antibodies.

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