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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 401-410 of 12,052 results

Spinal Cord InjuryTraumaRehabilitation

Traumatic cervical spinal cord injury in southeastern Norway: acute treatment, specialized rehabilitation referral and mortality

Frontiers in Neurology, 2024 • December 16, 2024

This population-based cohort study examined patients with traumatic cervical spinal cord injury (cSCI) in Southeastern Norway from 2015 to 2022, focusing on treatment approaches and outcomes. The stud...

KEY FINDING: Advanced age, particularly among octogenarians, was significantly associated with a lack of referral to specialized rehabilitation centers.

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Spinal Cord InjuryAccessibility

A Scoping Review on the Influence of Housing on the Health and Well-Being of People with a Spinal Cord Injury/Dysfunction

Healthcare, 2024 • December 16, 2024

This scoping review examined the current state of evidence for housing across the continuum for individuals with an SCI/D and has provided several critical insights and identified notable gaps in the ...

KEY FINDING: Inaccessible housing leads to lower autonomy, especially for those with more severe injuries, poorer quality of life, and reduced community participation.

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NeuroimagingNeurologyBrain Injury

Differential brain activity in patients with disorders of consciousness: a 3-month rs-fMRI study using amplitude of low-frequency fluctuation

Frontiers in Neurology, 2024 • December 13, 2024

This study used rs-fMRI and ALFF to examine brain activity differences in DoC patients with TBI and non-TBI, assessing the predictive value of these measures for consciousness improvement after SCS th...

KEY FINDING: Patients with TBI showed increased ALFF in the thalamus and anterior cingulate cortex, while the middle occipital lobe showed decreased ALFF.

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Spinal Cord InjuryNeurologyRehabilitation

Neurostimulation on lumbosacral nerves as a new treatment for spinal cord injury impairments and its impact on cortical activity: a narrative review

Frontiers in Human Neuroscience, 2024 • December 13, 2024

This review outlines the etiology, physiological consequences, and long-term impacts of SCI under neuromodulation therapies, focusing on the potential of the laparoscopic implantation of neuroprosthes...

KEY FINDING: The LION procedure has shown improvements in mobility, with some patients regaining walker-assisted gait, especially in their homes. Patients also became less dependent on adapted environments.

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Spinal Cord InjuryHealthcare

The Development of a Certification and Grading Procedure for German SCI Units

Healthcare, 2024 • December 13, 2024

The German-Speaking Paraplegic Society (DMGP) developed a certification and grading system for German SCI units to protect established centers and enable qualified reimbursement negotiations. The grad...

KEY FINDING: The grading system categorizes SCI units into four levels, from Level Ia (24/7 coverage for all SCI-related emergencies) to Level IIb (rehab only, no intensive care unit).

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Spinal Cord InjuryPulmonologyNeurology

Noninvasive Electrical Modalities to Alleviate Respiratory Deficits Following Spinal Cord Injury

Life, 2024 • December 13, 2024

Respiratory dysfunction following spinal cord injury (SCI) significantly impairs health and quality of life. Noninvasive electrical stimulation modalities, such as spinal cord transcutaneous stimulati...

KEY FINDING: Spinal cord transcutaneous stimulation (scTS) shows promise for respiratory rehabilitation in SCI patients.

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Spinal Cord InjuryCardiovascular ScienceRehabilitation

The Acute Effect of Hot Water Immersion on Cardiac Function in Individuals with Cervical Spinal Cord Injury

J. Clin. Med., 2024 • December 13, 2024

This study examined the impact of whole-body heat stress using head-out hot water immersion (HHWI) on cardiac function in individuals with cervical spinal cord injury (CSCI) and healthy participants. ...

KEY FINDING: In healthy participants, heat stress increased left atrial contractility, left ventricular dilatation, and left ventricular contractility.

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Spinal Cord InjuryImmunologyGenetics

Macropinocytosis enhances foamy macrophage formation and cholesterol crystallization to activate NLRP3 inflammasome after spinal cord injury

Redox Biology, 2025 • December 12, 2024

This study investigates the role of macropinocytosis in foam cell formation following spinal cord injury (SCI). It demonstrates that foam cells are primarily derived from macrophages and that macropin...

KEY FINDING: Foam cells formed after myelin debris internalization were predominantly macrophages rather than microglia after spinal cord injury.

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Spinal Cord InjuryRegenerative MedicineBiomedical

Application of Adipose Extracellular Matrix and Reduced Graphene Oxide Nanocomposites for Spinal Cord Injury Repair

Advanced Healthcare Materials, 2025 • December 12, 2024

The study evaluated an rGO-based nanocomposite supported by adipose decellularized ECM for spinal cord injury repair. The nanocomposite evoked a tissue-regenerative response, demonstrating the potenti...

KEY FINDING: adECM-rGO nanocomposites completely restored the integrity of the spinal cord after hemisection SCI in rats.

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Regenerative MedicineGenetics

Marcks and Marcks-­like 1 proteins promote spinal cord development and regeneration in Xenopus

eLife, 2024 • December 12, 2024

The study identifies Marcks and Marcksl1 as essential proteins for spinal cord development and regeneration in Xenopus laevis. Loss-of-function experiments demonstrated that Marcks and Marcksl1 are re...

KEY FINDING: Marcks and Marcksl1 are required for normal neurite formation during spinal cord development, acting redundantly.

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