Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 3,901-3,910 of 12,052 results
Journal of Taibah University Medical Sciences, 2023 • October 10, 2022
This study investigated the causes and consequences of neglected traumatic spinal cord injuries (TSCIs) in 18 patients who underwent surgical treatment more than 14 days after injury. The results show...
KEY FINDING: Delayed referral to a tertiary hospital was the most common cause of neglect in the studied patients.
Bioengineering, 2022 • October 9, 2022
The study investigates the therapeutic potential of human amniotic epithelial cell (hAEC)-derived neural-like cells delivered via a 3D-printed biomimetic scaffold for spinal cord injury (SCI) treatmen...
KEY FINDING: Human amniotic epithelial cells (hAECs) can be effectively induced into neural-like cells using a compound cocktail (BGVB), showing morphological changes and expression of neural cell markers.
Biomedicines, 2022 • October 8, 2022
This study evaluates the efficacy of an antibiotic-loaded ceramic-based bone graft substitute (HACaS+G) for treating infected non-unions in a rat model. The results indicate that HACaS+G is osteoinduc...
KEY FINDING: HACaS+G demonstrated osteoinductive properties, stimulating bone formation in both infected and non-infected conditions.
ibrain, 2022 • October 8, 2022
This case report describes a rare presentation of a thoracic epidural arteriovenous malformation (E-AVM) that mimicked acute transverse myelitis (ATM) in a 25-year-old male, leading to an initial misd...
KEY FINDING: Spinal epidural AVMs can mimic acute transverse myelitis, leading to misdiagnosis and delayed treatment.
Medicine, 2022 • October 7, 2022
This study used network pharmacology and molecular docking to investigate the mechanism of Buyang Huanwu Decoction (BYHWD) in treating spinal cord injury (SCI). The study identified key active compoun...
KEY FINDING: The study identified 109 active compounds and 5440 prediction targets from Buyang Huanwu Decoction, with 98 active components and 49 related prediction targets being strongly linked to Spinal Cord Injury.
Evidence-Based Complementary and Alternative Medicine, 2022 • October 7, 2022
This study investigates the analgesic effects of electroacupuncture (EA) on neuropathic pain in a chronic constriction injury (CCI) rat model. The research focuses on the role of GABAA receptors and m...
KEY FINDING: EA treatment relieves mechanical allodynia and thermal hyperalgesia in CCI rats, as demonstrated by increased MWT and TWL values compared to the CCI group.
Health and Quality of Life Outcomes, 2022 • October 7, 2022
This study investigates the role of mindfulness in the quality of life (QOL) of persons with spinal cord injury (PwSCI). It examines both the direct impact of mindfulness on QOL and its indirect effec...
KEY FINDING: Mindfulness significantly contributes to a higher quality of life for individuals with spinal cord injuries, even when considering other factors like age, employment, and injury severity.
Frontiers in Pharmacology, 2022 • October 7, 2022
This study investigated the neuroprotective effects of Andrographolide (Andro) on spinal cord injury (SCI) in rats. The findings suggest that Andro treatment can alleviate SCI by reducing apoptosis, o...
KEY FINDING: Andro treatment significantly improved tissue repair and functional recovery after SCI by reducing apoptosis, oxidative stress, and inflammation through the Nrf-2/HO-1 and NF-κB signaling pathways.
Computational Intelligence and Neuroscience, 2022 • October 6, 2022
The study aimed to evaluate the therapeutic effects of posterior injured vertebra column resection (PIVCR) and spinal shortening for thoracolumbar fractures associated with severe spinal cord injury (...
KEY FINDING: PIVCR and spinal shortening resulted in better postoperative canal decompression compared to simple posterior decompression and fixation.
Scientific Reports, 2022 • October 6, 2022
The study demonstrates a neuroprosthetic solution using electrical stimulation of the radial and median nerves to restore hand motor function in individuals with complete tetraplegia. Two participants...
KEY FINDING: Selective stimulation of nerve fascicles induced functional and powerful grasping movements that remained stable over 28 days of implantation.