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  4. Thoracic epidural arteriovenous malformation causing rapidly progressive myelopathy and mimicking an acute transverse myelitis: A case report

Thoracic epidural arteriovenous malformation causing rapidly progressive myelopathy and mimicking an acute transverse myelitis: A case report

ibrain, 2022 · DOI: 10.1002/ibra.12070 · Published: October 8, 2022

Cardiovascular ScienceNeurologyResearch Methodology & Design

Simple Explanation

This case report discusses a rare instance where a spinal arteriovenous malformation (AVM) in the epidural space mimicked acute transverse myelitis (ATM). This misdiagnosis led to initial treatment for ATM before the actual AVM was discovered. The patient, a 25-year-old man, experienced rapid paralysis and numbness in his lower limbs, initially diagnosed as ATM. However, further investigation revealed a mass, which was later identified as an AVM. Surgical intervention to remove the AVM led to significant improvement in the patient's motor and sensory functions. This highlights the importance of considering AVMs in cases of sudden spinal cord dysfunction.

Study Duration
12 months
Participants
One 25-year-old man
Evidence Level
Level 4: Case Report

Key Findings

  • 1
    Spinal epidural AVMs can mimic acute transverse myelitis, leading to misdiagnosis and delayed treatment.
  • 2
    MRI and angiography are crucial for the differential diagnosis of AVMs in patients presenting with acute spinal cord dysfunction.
  • 3
    Surgical removal of the AVM can result in significant neurological improvement in patients with spinal cord compression.

Research Summary

This case report describes a rare presentation of a thoracic epidural arteriovenous malformation (E-AVM) that mimicked acute transverse myelitis (ATM) in a 25-year-old male, leading to an initial misdiagnosis. The patient experienced rapidly progressive myelopathy. After surgical intervention involving posterior decompression and removal of the E-AVM, the patient showed significant improvement in motor and sensory function. The authors emphasize the importance of considering AVMs in the differential diagnosis of sudden or progressive spinal cord injuries and highlight the critical roles of angiography and MRI in diagnosing AVMs.

Practical Implications

Diagnostic Awareness

Clinicians should consider spinal AVMs in the differential diagnosis of acute spinal cord dysfunction, especially when initial treatments for conditions like ATM are ineffective.

Imaging Importance

Emphasize the use of both MRI and angiography for accurate diagnosis of spinal AVMs, as MRI findings can be atypical or misleading.

Surgical Intervention

Early surgical intervention is recommended for patients with rapidly progressing neurological deterioration due to spinal AVMs to prevent permanent damage and improve outcomes.

Study Limitations

  • 1
    Single case report limits generalizability.
  • 2
    Preoperative angiography was not performed.
  • 3
    Limited follow-up duration (12 months).

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