Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 361-370 of 12,052 results
Int. J. Mol. Sci., 2025 • December 30, 2024
This study evaluated the efficacy of long-term NLX-112 intervention starting from two weeks post-T8 contusive SCI for an additional six weeks. Our results indicate that NLX-112 treatment significantly...
KEY FINDING: NLX-112 treatment significantly improves locomotion in a dose-dependent fashion, suggesting a direct relationship between the amount of drug and the improvement in walking ability.
Am J Transl Res, 2024 • December 30, 2024
This review explores the pathogenesis and treatment of scoliosis in adult Type 1 Chiari malformation patients with syringomyelia (CIM-SM), highlighting the complexities of surgical intervention. Key a...
KEY FINDING: Adult CIM patients often have more severe clinical manifestations, including brainstem and cranial nerve compression, leading to scoliosis deformities being overlooked.
PLoS ONE, 2024 • December 30, 2024
This study evaluated the content validity of a prototype ABT tracking tool through cognitive debriefing interviews with clinicians and people with SCI/D who participate in ABT in a community-based set...
KEY FINDING: The ABT tracking tool was considered comprehensive and appropriate for individuals with SCI/D of all injury profiles.
Molecules, 2025 • December 29, 2024
This study explores the gastroprotective effects of methyl eugenol (ME) in a rat model of spinal cord injury (SCI). SCI often leads to gastric ulceration, and current treatments have adverse effects. ...
KEY FINDING: Methyl eugenol exhibits a dose-dependent gastroprotective effect against gastric damage induced by spinal cord injury in rats.
Cureus, 2024 • December 29, 2024
This case report presents a rare instance of bilateral foot drop following cervical decompression in a patient with tandem spinal stenosis, complicated by white cord syndrome. The patient's postoperat...
KEY FINDING: The patient experienced transient improvements post-cervical decompression but later developed delirium, worsening right-sided weakness, and bilateral foot drop.
Bioactive Materials, 2025 • December 27, 2024
This study developed a 3D bioprinted dynamic living construct that modulates encapsulated NSCs to self-organize into a functional neural network for spinal cord injury repair. The ECM-mimicking bioink...
KEY FINDING: The dynamic properties of the 3D bioprinted living fibers alleviate mechanical confinement on NSCs, enhancing their mechanosensing, spreading, migration, and matrix remodeling.
J. Imaging, 2025 • December 27, 2024
This study introduces a modified center-edge (CE) angle to improve the diagnosis of developmental dysplasia of the hip (DDH) in young children, as the standard CE angle is unreliable in this age group...
KEY FINDING: The modified CE angle (MCE) exhibited high sensitivity and specificity, comparable to the standard CE angle, for children under and over four years old.
Korean J Neurotrauma, 2024 • December 26, 2024
Acute SCI requires a multidisciplinary approach for optimal management, focusing on both primary and secondary injury processes. Surgical decompression within 24 hours and early neurointensive care ar...
KEY FINDING: Early decompressive surgery within 24 hours post-injury is widely supported for patients with spinal instability or cord compression, enhancing motor recovery, especially in incomplete SCI.
Clin. Pract., 2025 • December 26, 2024
Spinal cord injury (SCI) is defined as physical damage that alters the function and structure of the spinal cord. Traumatic causes, such as vehicle accidents, falls, and violence, account for 90% of S...
KEY FINDING: Early intensive care unit (ICU) monitoring improves patient prognosis, highlighting the importance of prompt ICU admission and early decompression surgery.
Biomolecules, 2025 • December 26, 2024
This study demonstrates that inhibiting IL-18 with a blocking antibody significantly improved motor functional recovery following SCI by reducing neuroinflammation, glial activation, and neuronal cell...
KEY FINDING: IL-18 expression significantly increased in the spinal cord after SCI, suggesting its involvement in the injury response.