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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 371-380 of 12,052 results

SurgeryTraumaOrthopedics

Association Between Trauma-Induced Vertebral Fractures and Motor Weakness in Patients With Diffuse Idiopathic Skeletal Hyperostosis

Cureus, 2024 • December 26, 2024

Approximately half of the DISH-related spinal fractures were accompanied by neurological symptoms, and 41% of the patients exhibited paralysis. Severe spinal canal stenosis on sagittal CT and MR was i...

KEY FINDING: Approximately half of DISH-related spinal fractures were accompanied by neurological symptoms, and 41% of the patients exhibited paralysis.

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Spinal Cord InjuryRegenerative Medicine

Induced Neural Stem Cell Transplantation in Spinal Cord Injury: Present Status and Next Steps

Korean J Neurotrauma, 2024 • December 26, 2024

This review examines iNSCs as promising candidates for SCI treatment, highlighting their potential for neural regeneration and integration with host tissue. Key challenges in translating iNSC therapie...

KEY FINDING: iNSCs demonstrate potential for direct neural regeneration and integration with host spinal cord tissue, offering advantages over other cellular therapies.

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TraumaPublic Health

Effectiveness of Integrated Trauma System Implementation on Road Traffic Fatalities and Injuries in the North of Iran Using an Interrupted Time Series Analysis

Journal of Research in Health Sciences, 2025 • December 25, 2024

This study evaluated the effectiveness of an integrated trauma system (ITS) in reducing road traffic crashes (RTCs), injuries, and fatalities in Guilan province, Northern Iran, from 2015 to 2019. The ...

KEY FINDING: The study found that in Guilan, the daily average number of RTCs decreased significantly after the implementation of the ITS, from 38.4 to 30.8.

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Spinal Cord InjuryRehabilitationMusculoskeletal Medicine

Review of osteokines in spinal cord injury: potential biomarkers during rehabilitation

Journal of Orthopaedic Surgery and Research, 2025 • December 25, 2024

This review summarizes recent findings regarding bone loss after SCI, changes in osteokines, and the effect of rehabilitation therapies, with a particular emphasis on the local and systemic regulatory...

KEY FINDING: Osteoporosis is common after SCI, especially in the distal femur and proximal tibia, increasing fracture risk.

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Spinal Cord InjuryNeurologyBiomedical

Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats

Bioactive Materials, 2025 • December 24, 2024

This study explores the neuro-reparative properties of 3D porous reduced graphene oxide (rGO) scaffolds when chronically implanted in complete transected rats (T9-T10). Electrophysiological recordings...

KEY FINDING: rGO scaffolds create a permissive environment that allows the invasion of functional axonic processes from neurons located in brainstem nuclei with motor function in a rat model of complete thoracic transection.

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NeurologyPain ManagementSurgery

Complex Regional Pain Syndrome: Diagnosis, Pathophysiology, and Treatment Approaches

Cureus, 2024 • December 24, 2024

Complex regional pain syndrome (CRPS) is a chronic pain condition characterized by significant sensory, motor, and autonomic dysfunction, often following trauma or nerve injury. The management of CRPS...

KEY FINDING: CRPS involves a complex interplay of peripheral and central mechanisms, neurogenic and classic inflammation, and potential autoimmune and psychological influences.

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SurgeryOrthopedicsBiomedical

Long-Term Outcomes of Nano-Hydroxyapatite/Polyamide 66 Strut in Thoracolumbar Burst Fractures

Med Sci Monit, 2024 • December 24, 2024

Long-term results of clinical and radiographic assessment of the n-HA/PA66 strut in treating thoracolumbar burst fractures could achieve satisfactory solid anterior support, effective restoration of i...

KEY FINDING: At the final FU, the patients of ASIA B, C, and D recovered to E.

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Spinal Cord InjuryBioinformaticsRehabilitation

Using Artificial Intelligence in the Comprehensive Management of Spinal Cord Injury

Korean J Neurotrauma, 2024 • December 24, 2024

AI technology, especially machine learning, is revolutionizing the management of spinal cord injuries by enhancing diagnosis, treatment, prognosis, and rehabilitation. Deep learning models improve dia...

KEY FINDING: AI improves diagnostic accuracy by identifying subtle lesions or fiber tract disruptions often missed by human radiologists and integrates multimodal data for comprehensive diagnosis.

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Spinal Cord InjuryPain ManagementResearch Methodology & Design

Research progress in neuropathic pain after spinal cord injury: a bibliometric study from 2013 to 2024

Frontiers in Neurology, 2024 • December 24, 2024

This study provides a bibliometric analysis of neuropathic pain (NP) research after spinal cord injury (SCI) from 2013 to 2024, using CiteSpace to analyze publications, journals, authors, references, ...

KEY FINDING: There was an overall upward trend in the number of publications on neuropathic pain after spinal cord injury between 2013 and 2024.

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NeurologyRehabilitationPublic Health

Quality of life and subjective well-being comparison between traumatic, nontraumatic chronic spinal cord injury, and healthy individuals in China

PeerJ, 2024 • December 23, 2024

This study compared the quality of life, health, and subjective well-being of individuals with T-SCI and NT-SCI. The results revealed significant differences in QoL and health between the two groups, p...

KEY FINDING: Individuals with NT-SCI experience significantly worse overall health outcomes compared to those with T-SCI.

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