Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 321-330 of 12,052 results
Trauma Surg Acute Care Open, 2025 • January 1, 2025
This retrospective study evaluated the association between prophylactic iNPPV and the incidence of pneumonia in patients with acute CSCIs. The study included 94 patients diagnosed with CSCIs with ASIA...
KEY FINDING: Prophylactic iNPPV was associated with a lower incidence of pneumonia compared to usual care in patients with acute CSCIs.
Cell Transplantation, 2025 • January 1, 2025
This study evaluated the effectiveness of combined intrathecal injection of Schwann cells (SCs) and bone marrow–derived mesenchymal stem cells (BMSCs) in improving SCI-induced neuropathic pain and qua...
KEY FINDING: Significant reductions were observed in pain interference with daily activities, mood, and sleep in the treatment group compared to the control group after 6 months.
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2025 • January 1, 2025
This study investigates the effects of intrathecal transplantation of human umbilical cord mesenchymal stem cells (hUCMSCs) in a rat model of spinal cord injury (SCI). The results demonstrated that hU...
KEY FINDING: hUCMSC transplantation improved motor function in rats with SCI, particularly on days 7 and 14 post-injury, as measured by the BBB locomotor rating scale and Rivlin inclined plane test.
Clinics, 2025 • January 1, 2025
This study evaluated the use of human umbilical cord blood-derived mononuclear cells (UCB-MNCs) in treating spinal cord injury (SCI) in mice, focusing on histological changes and motor function recove...
KEY FINDING: Umbilical cord blood-derived mononuclear cells-treated groups exhibited significant reductions in necrosis, hemorrhage, and degeneration compared to controls.
Braz J Cardiovasc Surg, 2025 • January 1, 2025
This retrospective study compared hemiarch repair and total arch replacement (TAR) for acute type A aortic dissection (ATAAD) in 107 patients. The primary outcomes were stroke rate, spinal cord injur...
KEY FINDING: The study found no significant differences in early mortality, stroke rate, or spinal cord injury between patients undergoing hemiarch repair and those undergoing total arch replacement.
Scientific Reports, 2025 • January 1, 2025
The study investigated the role of perineuronal nets (PNNs), formed by extracellular matrix (ECM) molecules, in fear memory processes using mice lacking brevican, neurocan, tenascin-C, and tenascin-R ...
KEY FINDING: Mice lacking brevican, neurocan, tenascin-C, and tenascin-R (4x KO) exhibited impaired fear memory consolidation, indicated by their inability to retrieve previously learned fear memories.
Journal of Feline Medicine and Surgery, 2025 • January 1, 2025
This retrospective study evaluated 23 cats with airgun spinal cord injuries (SCIs) between 1998 and 2022. The study aimed to describe these injuries and evaluate outcomes related to surgical or conser...
KEY FINDING: Airgun spinal injuries in cats often result in severe mobility and micturition disorders.
Global Spine Journal, 2025 • January 1, 2025
This study evaluated the ability of ChatGPT-4o and Google Gemini Advanced to adhere to the 2022 American College of Surgeons (ACS) Best Practice Guidelines for spinal injury management. The AI models ...
KEY FINDING: ChatGPT-4o was correct on 73.07% of the questions, while Gemini Advanced was correct on 69.23%. Most incorrect answers were due to not providing enough information rather than giving wrong information.
BMJ Open Respir Res, 2025 • January 1, 2025
This study reports on 359 adults established on domiciliary MIE. The range of prescribed settings is narrow, reflecting the limited evidence base in this field and the need to better understand optima...
KEY FINDING: The most common diagnostic groups using MIE were congenital neuromuscular disease (26%), spinal cord injury (23%), and amyotrophic lateral sclerosis (23%).
Scientific Reports, 2025 • January 1, 2025
This study assessed the accuracy of a radiomics approach, based on machine learning and utilizing conventional MRI, in predicting the prognosis of patients with SCI. The random forest (RF) combined wi...
KEY FINDING: A combined model using ResNet34 and radiomics demonstrated excellent performance with an accuracy of 0.800 and an AUC of 0.893 in predicting long-term motor function outcomes.