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  4. Report on the clinical outcomes of using postural drainage with intervertebral space as the main focus for managing thoracolumbar tuberculosis

Report on the clinical outcomes of using postural drainage with intervertebral space as the main focus for managing thoracolumbar tuberculosis

Medicine, 2025 · DOI: http://dx.doi.org/10.1097/MD.0000000000041204 · Published: January 1, 2025

PulmonologyOrthopedicsSpinal Disorders

Simple Explanation

This study explores a treatment method for thoracolumbar tuberculosis (TB) focusing on the intervertebral space, which is often difficult to treat with conventional methods. The standard treatment of antibiotics is unable to penetrate avascular intervertebral discs. Conventional surgery is known for trauma and slow healing. The method involves postural drainage, where the patient's position is adjusted to help drain infected fluid from the intervertebral space. Catheter placement locations were determined based on clinical imaging results, and percutaneous catheter placement was performed with the assistance of foraminoscopy. The study reports on eight patients who underwent this treatment, showing significant improvements in various clinical indicators and no recurrence of TB during the follow-up period. The utilization of positional drainage in the intervertebral space, coupled with chemotherapy, has demonstrated encouraging clinical results.

Study Duration
7.75 ± 10.19 months
Participants
8 patients with thoracolumbar spinal TB
Evidence Level
Level 4: Case Series

Key Findings

  • 1
    Postural drainage focusing on the intervertebral space, combined with chemotherapy, led to significant improvements in erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), Visual Analogue Scale (VAS) score, American Spinal Cord Injury Association (ASIA) score, and Oswestry functional index.
  • 2
    The average operation time for the postural drainage procedure was approximately 44 minutes, with minimal blood loss.
  • 3
    During a follow-up period ranging from 36 to 122 months, none of the patients experienced a recurrence of tuberculosis.

Research Summary

This clinical case report assesses the outcomes of postural drainage targeting the intervertebral space, combined with chemotherapy, for treating thoracolumbar tuberculosis. Eight cases of thoracolumbar spinal TB were treated by postural drainage with the intervertebral space as the treatment center The study found significant improvements in inflammatory markers, pain levels, neurological function, and functional ability following the treatment. Significant improvements were observed in erythrocyte sedimentation rate, C-reactive protein, Visual Analogue Scale score, American Spinal Cord Injury Association score, and Oswestry functional index The authors conclude that postural drainage of the intervertebral space, along with chemotherapy, shows promising clinical results and may be a suitable treatment approach. The utilization of positional drainage in the intervertebral space, coupled with chemotherapy, has demonstrated encouraging clinical results

Practical Implications

Clinical Practice

The study suggests that postural drainage focused on the intervertebral space can be considered as a treatment option for thoracolumbar tuberculosis, particularly when the intervertebral space is involved.

Surgical Technique

The study highlights a minimally invasive surgical technique for abscess drainage in spinal TB, which may reduce trauma and improve recovery compared to traditional surgery.

Future Research

The authors recommend further research with larger sample sizes and multi-center studies to confirm the advantages and disadvantages of this treatment method.

Study Limitations

  • 1
    Small sample size (8 patients)
  • 2
    Retrospective study design
  • 3
    Lack of a control group

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