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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Latest Research Summaries

Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.

Showing 11,981-11,990 of 12,052 results

Spinal Cord InjuryAssistive TechnologyNeurorehabilitation

Robot Application of Elastic Fields to the Pelvis of the Spinal Transected Rat: a Tool for Detailed Assessment and Rehabilitation

Conf Proc IEEE Eng Med Biol Soc, 2006 • January 1, 2006

The study examines robotic rehabilitation and assessment of spinalized rats using robot-applied forces at the pelvis as a prelude to a neurorobotic brain-machine interface (BMI). The system applies an...

KEY FINDING: Robotic training led to significant improvements in treadmill locomotor stepping over time in adult spinalized rats.

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NeurologyPain Management

A case of post-traumatic cervicogenic headache treated by cervical cord stimulation

J Headache Pain, 2005 • December 15, 2005

This case report describes a 26-year-old woman with post-traumatic cervicogenic headache treated with cervical cord stimulation after failing medical and surgical interventions. The patient experience...

KEY FINDING: Cervical cord stimulation was effective in improving cervicogenic headache in a patient who had undergone cervical discectomy and fusion.

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Spinal Cord InjuryNeurologyRehabilitation

Spinal Cord-Transected Mice Learn to Step in Response to Quipazine Treatment and Robotic Training

The Journal of Neuroscience, 2005 • December 14, 2005

The study demonstrates that complete spinal cord-transected mice can be robotically trained to step, whereas manual training, as performed in the present study, is ineffective. Quipazine (0.5 mg/kg) e...

KEY FINDING: Manual training alone was ineffective in improving stepping performance in complete spinal cord-transected mice.

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Spinal Cord InjuryNeurologyGenetics

Differential activation of astrocytes and microglia after spinal cord injury in the fetal rat

Eur Spine J, 2006 • November 16, 2005

This study examined glial reactions following spinal cord injury in fetal rats compared to adult rats, focusing on astrocytes and microglia. The findings indicated that fetal rats do not develop scar ...

KEY FINDING: Scar formation was observed in adult rats' spinal cords after injury, but not in fetal rats.

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Spinal Cord InjuryRegenerative MedicineBiomedical

Development of a tissue-engineered composite implant for treating traumatic paraplegia in rats

Eur Spine J, 2006 • November 15, 2005

This study assessed a new composite implant to induce regeneration of injured spinal cord in paraplegic rats following complete cord transection. Implants of adult human NOM cells were implanted into ...

KEY FINDING: Rats with complete spinal cord transection showed partial recovery of function after implantation with a composite implant containing either adult human nasal olfactory mucosa cells or human embryonic spinal cord cells.

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Spinal Cord InjuryMental HealthPain Management

Cluster Analysis and Chronic Pain: An Empirical Classification of Pain Subgroups in a Spinal Cord Injury Sample

Rehabil Psychol, 2005 • November 1, 2005

The study aimed to identify homogeneous pain subgroups within a spinal cord injury (SCI) population using cluster analysis based on pain intensity, pain interference, and depression. Multivariate clus...

KEY FINDING: Four distinct SCI pain subgroups were identified: Low Pain, Positive Adaptation to Pain, Minimal Distress, and Chronic Pain Syndrome.

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PhysiologyNeurologyRehabilitation

Intraspinal microstimulation preferentially recruits fatigue-resistant muscle fibres and generates gradual force in rat

J Physiol, 2005 • October 20, 2005

This study compared muscle recruitment characteristics of intraspinal microstimulation (ISMS) and nerve cuff stimulation (NCS) in rats. The results showed that ISMS preferentially recruited fatigue-re...

KEY FINDING: ISMS preferentially recruits fatigue-resistant (FR) fibers compared to NCS, especially at higher stimulation amplitudes.

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Pain ManagementResearch Methodology & Design

Lack of interchangeability between visual analogue and verbal rating pain scales: a cross sectional description of pain etiology groups

BMC Medical Research Methodology, 2005 • October 4, 2005

This cross-sectional study examined the interchangeability of the Visual Analogue Scale (VAS) and the Verbal Rating Scale (VRS) in assessing pain intensity among patients with chronic/idiopathic, noci...

KEY FINDING: There was an overlapping of VAS records relative to the VRS categories in all pain groups, indicating a lack of direct correspondence between the two scales.

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Spinal Cord InjuryRehabilitationMusculoskeletal Medicine

Bone Mineral Density After Spinal Cord Injury: A Reliable Method for Knee Measurement

Arch Phys Med Rehabil, 2005 • October 1, 2005

This study focused on developing and validating a reliable method for measuring bone mineral density (BMD) in the knees of individuals with spinal cord injury (SCI) using dual-energy x-ray absorptiome...

KEY FINDING: The study established a highly reliable method for analyzing knee BMD using DXA scans, indicated by high intraclass correlation coefficients (ICC).

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Spinal Cord InjuryRegenerative MedicineNeurology

Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice

PNAS, 2005 • September 27, 2005

The study investigated the potential of human central nervous system stem cells (hCNS-SCns) to promote recovery in spinal cord-injured mice. The researchers found that hCNS-SCns survived, migrated, an...

KEY FINDING: hCNS-SCns survive, engraft, differentiate, and are associated with locomotor improvements after traumatic spinal cord injury in NOD-scid mice.

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