Browse our collection of 12,052 research summaries, all carefully curated and simplified for the spinal cord injury community.
Showing 11,971-11,980 of 12,052 results
TheScientificWorldJOURNAL, 2006 • February 17, 2006
The objective of this article was to determine the current practice on amikacin dosing and monitoring in spinal cord injury patients from spinal cord physicians and experts. This study shows that ther...
KEY FINDING: Clinical practice varies considerably across spinal units regarding amikacin administration, with some using once-daily dosing and others using divided doses.
The Journal of Neuroscience, 2006 • February 8, 2006
This study demonstrates that transplanted GFP-OECs can remyelinate demyelinated spinal cord axons and establish structurally intact nodes of Ranvier. The remyelinated axons exhibit appropriate cluster...
KEY FINDING: Transplanted olfactory ensheathing cells (OECs) remyelinate demyelinated axons in the spinal cord and promote the formation of structurally intact nodes of Ranvier.
Disabil Rehabil, 2006 • January 30, 2006
This study evaluated the effectiveness of follow-up questions for the SF-12 questionnaire in assessing physical function in individuals with complete SCI. The results showed that the follow-up questio...
KEY FINDING: The SF-12 follow-up questions revealed differences in physical function among subjects with complete SCI that were not apparent with the original SF-12 items. Using the new questions, subject scores approximated population normative values.
The Journal of Neuroscience, 2006 • January 25, 2006
This study investigates the contribution of dorsal progenitors to cortical myelination by ablating Olig2, a key gene for oligodendrocyte specification, in these cells. The results demonstrate that dor...
KEY FINDING: Ablation of Olig2 in dorsal progenitors leads to a near-complete absence of myelination in the cortex during early postnatal stages.
British Journal of Cancer, 2006 • January 24, 2006
This retrospective audit assessed the care of 174 patients with MSCC at a UK cancer centre over a 12-month period, revealing shortcomings in pain assessment, patient mobility, and rehabilitation plann...
KEY FINDING: The common primary tumor diagnoses were lung (29%), prostate (19%), and breast (13%).
BMC Neuroscience, 2006 • January 24, 2006
The study investigated the effects of LPS-induced inflammation on the expression of growth-associated genes in corticospinal neurons and the potential for axonal regeneration after spinal cord injury....
KEY FINDING: Application of LPS induced a gradient of inflammation throughout the motor cortex.
PNAS, 2006 • January 17, 2006
This study demonstrates the role of Cdk5 in nociceptive signaling. It identifies the expression of Cdk5 and its activator p35 in nociceptive neurons and shows that this expression is modulated during ...
KEY FINDING: Cdk5 and p35 are expressed in pain-sensing neurons (nociceptors) within the dorsal root ganglia (DRG), trigeminal ganglia (TG), and spinal cord (SC).
BMC Neuroscience, 2006 • January 12, 2006
The study investigates the expression and function of ZAS3, a zinc finger protein, in the nervous system and its relationship with NF-κB after peripheral nerve injury. Results show that ZAS3 is expres...
KEY FINDING: ZAS3 is expressed in specific regions of the central and peripheral nervous system, including the trigeminal ganglion, hippocampal formation, dorsal root ganglia, and motoneurons.
Eur Spine J, 2006 • January 1, 2006
The study used a biofidelic whole cervical spine model to simulate frontal impacts at varying severities (4, 6, 8, and 10 g) to quantify canal pinch diameter (CPD) narrowing. Dynamic impact CPD narrow...
KEY FINDING: Frontal impact caused significant dynamic CPD narrowing at C0-dens, C2-C3, and C6-C7 intervertebral levels.
J Rehabil Res Dev, 2006 • January 1, 2006
This study used a musculoskeletal model of the legs and trunk to determine which muscles to target with the new system in order to maximize the range of postures that can be statically maintained, whi...
KEY FINDING: The prime muscle targets should be the medial gastrocnemius, tibialis anterior, vastus lateralis, semimembranosus, gluteus maximus, gluteus medius, adductor magnus, and erector spinae.