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  4. Bone Mineral Density After Spinal Cord Injury: A Reliable Method for Knee Measurement

Bone Mineral Density After Spinal Cord Injury: A Reliable Method for Knee Measurement

Arch Phys Med Rehabil, 2005 · DOI: 10.1016/j.apmr.2005.06.001 · Published: October 1, 2005

Spinal Cord InjuryRehabilitationMusculoskeletal Medicine

Simple Explanation

Osteoporosis is a common issue after spinal cord injury (SCI), leading to bone loss and increased fracture risk, particularly in the legs. This study aimed to develop a reliable way to measure bone density in the knees of people with SCI, comparing their bone density to that of people without SCI. The researchers found a reliable method for measuring bone density in the knee, and confirmed that individuals with SCI had lower bone density in their hips and knees compared to the control group.

Study Duration
Not specified
Participants
11 subjects with complete SCI and 11 able-bodied control subjects
Evidence Level
Criterion standard and masked comparison

Key Findings

  • 1
    The study established a highly reliable method for analyzing knee BMD using DXA scans, indicated by high intraclass correlation coefficients (ICC).
  • 2
    Individuals with SCI exhibited significantly lower BMD in their hips and knees compared to able-bodied controls, but no difference was found in lumbar spine BMD.
  • 3
    A moderate correlation was found between hip BMD and distal femur BMD, suggesting that hip BMD can predict distal femur BMD in this population.

Research Summary

This study focused on developing and validating a reliable method for measuring bone mineral density (BMD) in the knees of individuals with spinal cord injury (SCI) using dual-energy x-ray absorptiometry (DXA). The research demonstrated that the newly developed protocol for analyzing knee BMD is highly reliable and reproducible. The study compared BMD measurements of the spine, hip, and knee between people with SCI and able-bodied controls. The key findings indicated that individuals with SCI have significantly lower BMD in their hips and knees compared to controls, while lumbar spine BMD did not differ significantly between the groups. Furthermore, hip BMD was found to be moderately predictive of distal femur BMD.

Practical Implications

Improved Fracture Risk Assessment

The reliable knee BMD measurement method allows for more accurate assessment of fracture risk in SCI patients.

Targeted Rehabilitation Strategies

Understanding BMD at fracture-prone sites can help rehabilitation specialists design targeted interventions to maintain skeletal integrity.

Enhanced Treatment Monitoring

The validated protocol enables better monitoring of the efficacy of anti-osteoporosis treatments in SCI patients.

Study Limitations

  • 1
    Small sample size
  • 2
    Potential for error in longitudinal assessments
  • 3
    Focus on between-rater reliability rather than within-rater

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