Spinal Cord Injury Research

KEY FINDING: Epidural stimulation can cause a rise in blood pressure and prevent orthostatic hypotension by inducing vasoconstriction below the level of injury.

KEY FINDING: Both CX717 and CX1739 increased diaphragm EMG output ipsilateral to C2Hx during both baseline breathing and acute respiratory challenge at 4 days post-injury.

KEY FINDING: Regenerative rehabilitation can be categorized into conditioning/reconditioning, functional training, and physical exercise, which are indispensable for enhancing functional recovery achieved using stem cell therapies.

KEY FINDING: DPP+ dogs in the study group had an ambulation rate of 99.4% compared to 75.8% in the control group, demonstrating a statistically significant difference (p < 0.001).

KEY FINDING: Healthy eating for individuals with SCI revolves around types of food, amounts/portions, mindful eating, and eating to enhance health, with specific requests for tailored dietary information.

KEY FINDING: EMF stimulation significantly attenuated hyperalgesia and allodynia to thermal, electrical, and chemical stimuli from 6 weeks onwards in rats with complete SCI.

KEY FINDING: Subthreshold TSCS facilitates hand muscle responses to motor cortex stimulation, with a tendency toward greater facilitation when TSCS is timed to arrive at cervical synapses simultaneously or up to 10 milliseconds after cortical stimulus arrival.

KEY FINDING: Robot-assisted gait resulted in lower peak foot pressure compared to independent over-ground gait in both strong and weak legs.

KEY FINDING: A 64-year-old male with a spinal cord injury since 1981 and a history of recurrent left-sided kidney stones developed a locally advanced renal squamous cell carcinoma (RSCC).

KEY FINDING: Silencing spared LAPNs post-SCI improved locomotor function, including paw placement order and timing.