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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Spinal Cord Injury Research

Browse the latest research summaries in the field of spinal cord injury for spinal cord injury patients and caregivers.

Showing 2,551-2,560 of 7,812 results

Spinal Cord InjuryRehabilitationBiomechanics

Publisher Correction: Co‑contraction of ankle muscle activity during quiet standing in individuals with incomplete spinal cord injury is associated with postural instability

Scientific Reports, 2021 • October 1, 2021

This is a publisher correction for an article on ankle muscle co-contraction and postural instability in individuals with incomplete spinal cord injury (iSCI). The correction addresses errors in Figur...

KEY FINDING: The error in Figure 6(a) involved mislabeling of simulated groups in the EO and EC conditions.

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Spinal Cord InjuryPharmacologyNeurology

Novel optimized drug delivery systems for enhancing spinal cord injury repair in rats

DRUG DELIVERY, 2021 • November 15, 2021

The study successfully designed and synthesized two novel optimized drug delivery microspheres, Lap/MS@Mel and PM/MS@Mel, for treating spinal cord injury in rats. The Lap/MS@Mel system facilitates pro...

KEY FINDING: Lap/MS@Mel hydrogels continuously released melatonin for at least 28 days in vitro, showing a more stable sustained release and better neural recovery ability in SCI rats.

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Spinal Cord InjuryRehabilitation

Benefits and interval training in individuals with spinal cord injury: A thematic review

The Journal of Spinal Cord Medicine, 2022 • January 1, 2022

This thematic review examined the benefits and practicality of high-intensity interval training (HIIT) for individuals with spinal cord injury (SCI), focusing on exercises like arm crank ergometry (AC...

KEY FINDING: HIIT protocols generally showed greater improvements in cardiovascular and metabolic measures, or demonstrated improvements with shorter time commitments, compared to moderate-intensity continuous training (MICT).

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Spinal Cord InjuryRehabilitation

Validity and Reliability of Surface Electromyography Features in Lower Extremity Muscle Contraction in Healthy and Spinal Cord–Injured Participants

Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021

The purpose of this study was to explore the feasibility of using SEMG time-domain features to quantify volitional effort in the lower extremities of healthy individuals and SCI participants. In this ...

KEY FINDING: In healthy participants, SEMG features correlated well with torque (TA: ρ > 0.92; SOL: ρ > 0.94) and showed high reliability (ICCmean = 0.90; range, 0.72-0.99).

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Spinal Cord InjuryNeurology

Spinal cord imaging markers and recovery of standing with epidural stimulation in individuals with clinically motor complete spinal cord injury

Exp Brain Res, 2022 • January 1, 2022

This study investigated the relationship between spared spinal cord tissue, as measured by MRI, and standing ability with spinal cord epidural stimulation (scES) in individuals with clinically motor c...

KEY FINDING: Total volume of spared tissue was related to left, right, and bilateral lower limb extension.

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Spinal Cord InjuryAssistive TechnologyRehabilitation

Exoskeleton use in acute rehabilitation post spinal cord injury: A qualitative study exploring patients’ experiences

The Journal of Spinal Cord Medicine, 2022 • January 1, 2022

This qualitative study explored the experiences of patients with acute spinal cord injuries (SCI) using robotic exoskeletons as part of their inpatient rehabilitation. The study aimed to understand th...

KEY FINDING: Participants experienced psychological benefits such as improved mood, increased hope, and the joy of eye-level contact while using the exoskeleton.

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Spinal Cord InjuryOrthopedicsRehabilitation

Shoulder Pain Prevention Program for Manual Wheelchair Users With Paraplegia: A Randomized Clinical Trial

Top Spinal Cord Inj Rehabil, 2021 • October 1, 2021

The study evaluated the effectiveness of a Shoulder Pain Prevention Program (SPPP) in reducing shoulder pain onset in manual wheelchair users with paraplegia over 3 years, comparing two SPPP formats (...

KEY FINDING: SPPPs reduced shoulder pain onset prevalence regardless of instruction format. SP onset was identical in the two SPPPs but was significantly lower at 18 and 36 months in both groups compared to controls.

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Spinal Cord InjuryGastroenterologyRehabilitation

Longitudinal Trends and Prevalence of Bowel Management in Individuals With Spinal Cord Injury

Top Spinal Cord Inj Rehabil, 2021 • January 1, 2021

This study examined long-term bowel management trends in individuals with SCI using the NSCIMS database, revealing an initial increase in dependence at discharge followed by a shift towards greater in...

KEY FINDING: The need for total assistance with bowel management at discharge significantly increased over time (1988-2016).

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Spinal Cord InjuryRegenerative MedicineNeurology

Considering the Cellular Composition of Olfactory Ensheathing Cell Transplants for Spinal Cord Injury Repair: A Review of the Literature

Frontiers in Cellular Neuroscience, 2021 • November 17, 2021

This review summarizes the current literature relating to the composition, purity, and cell dose of OEC cultures used for transplant-mediated repair of SCI. OEC transplants are not very well character...

KEY FINDING: Successful transplant-mediated repair appeared to be possible using both low and high proportions of OECs in olfactory transplants.

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Spinal Cord InjuryRehabilitation

Comparison of the functional and cardiovascular effects of home-based versus supervised hospital circuit training exercises in male wheelchair users with chronic paraplegia

Turk J Phys Med Rehab, 2021 • September 1, 2021

This study compared the effectiveness of home-based versus supervised hospital circuit training exercises (CTEs) on functional and cardiovascular outcomes in male wheelchair users with chronic paraple...

KEY FINDING: Both supervised and home-based circuit training exercises improved upper extremity strength, cardiovascular endurance, and lipid profile in men with paraplegia.

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