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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Spinal Cord Injury Research

Browse the latest research summaries in the field of spinal cord injury for spinal cord injury patients and caregivers.

Showing 2,531-2,540 of 7,812 results

Spinal Cord InjuryNeurologyRehabilitation

Non-Invasive Neuromodulation and Rehabilitation to Promote Functional Restoration In Persons with Spinal Cord Injury

Curr Opin Neurol, 2021 • December 1, 2021

Clinically accessible modalities have great potential value as adjuncts to conventional therapeutic protocols due to their ease of application, cost effectiveness, and demonstrated neuromodulatory and...

KEY FINDING: Clinically accessible neuromodulatory modalities have the potential to augment therapeutic protocols.

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Spinal Cord InjuryNeurologyNeuroplasticity

A New Paired Associative Stimulation Protocol with High-Frequency Peripheral Component and High-Intensity 20 Hz Repetitive Transcranial Magnetic Stimulation—A Pilot Study

International Journal of Environmental Research and Public Health, 2021 • October 26, 2021

This pilot study investigated a new paired associative stimulation (PAS) protocol combining high-frequency peripheral nerve stimulation (PNS) with high-intensity 20 Hz repetitive transcranial magnetic...

KEY FINDING: The new three-pulse PAS protocol induced the strongest MEP potentiation 60 minutes after stimulation compared to other protocols.

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Spinal Cord InjuryAssistive TechnologyBiomechanics

Towards a Mobile Gait Analysis for Patients with a Spinal Cord Injury: A Robust Algorithm Validated for Slow Walking Speeds

Sensors, 2021 • November 6, 2021

This study introduces a sensor-based gait analysis algorithm designed specifically for SCI patients, utilizing shank-mounted inertial sensors and personalized thresholds for step and gait event detect...

KEY FINDING: The sensor-based algorithm performs similarly well for both SCI patients and healthy controls.

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Spinal Cord InjuryPharmacologyPain Management

Emerging Evidence for Intrathecal Management of Neuropathic Pain Following Spinal Cord Injury

Frontiers in Pain Research, 2022 • July 28, 2022

This review explores the emerging evidence for intrathecal management of neuropathic pain following spinal cord injury (SCI). It highlights the challenges in treating neuropathic pain in SCI patients ...

KEY FINDING: Neuropathic pain after SCI involves complex mechanisms including neuronal excitability, glial dysregulation, and chronic inflammation.

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Spinal Cord InjuryRegenerative MedicineNeurology

Oscillating field stimulation promotes axon regeneration and locomotor recovery after spinal cord injury

Neural Regeneration Research, 2022 • November 12, 2021

This study investigates the effect of oscillating field stimulation (OFS) on axonal regeneration, astrocyte proliferation, and astrocyte reorientation after spinal cord injury (SCI), as well as the re...

KEY FINDING: Continuous OFS for more than 6 weeks effectively promotes motor function recovery in rats with spinal cord injury.

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Spinal Cord InjurySurgeryBioinformatics

Topological network analysis of patient similarity for precision management of acute blood pressure in spinal cord injury

eLife, 2021 • November 16, 2021

Intra-­operative monitoring records (MAP, HR) and neurological outcome data were extracted and curated from two Level 1 trauma centers. A final cohort of 118 patients was included The exploratory netw...

KEY FINDING: Time outside of an optimum MAP range (hypotension or hypertension) during surgery was associated with lower likelihood of neurological recovery at hospital discharge.

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Spinal Cord InjuryAssistive TechnologyRehabilitation

Rehabilitation of Acute Vs. Chronic Patients With Spinal Cord Injury With a Neurologically Controlled Hybrid Assistive Limb Exoskeleton: Is There a Difference in Outcome?

Frontiers in Neurorobotics, 2021 • October 27, 2021

This study assessed the impact of HAL-assisted BWSTT on functional and motor recovery in acute and chronic SCI patients. The study found that both acute and chronic participants benefited from 12 week...

KEY FINDING: Both acute and chronic SCI patients showed significant improvements in walking ability after 12 weeks of HAL-assisted bodyweight supported treadmill training (BWSTT).

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Spinal Cord InjuryNeurologyMedical Imaging

MRI metrics at the epicenter of spinal cord injury are correlated with the stepping process in rhesus monkeys

Exp. Anim., 2022 • April 1, 2022

This study investigates the correlation between MRI metrics and gait parameters in rhesus monkeys after spinal cord injury (SCI) to predict long-term functional outcomes. The findings demonstrate that...

KEY FINDING: Residual tissue SCA at the injury epicenter and residual tissue FA/remote normal-like tissue FA were correlated with the early-stage PS and GS.

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Spinal Cord InjuryNeurology

Transcutaneous spinal cord stimulation and motor responses in individuals with spinal cord injury: A methodological review

PLOS ONE, 2021 • November 18, 2021

This review separated studies utilising tSCS into two broad categories: studies evaluating neurophysiological properties of stimulation at a spinal level and those using tSCS as a therapeutic modality...

KEY FINDING: The overall quality of evidence was deemed to be poor-to-fair based on the Downs and Black Quality Checklist criteria.

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Spinal Cord InjuryRehabilitationPublic Health

A one-year prospective study on the occurrence of traumatic spinal cord injury and clinical complications during hospitalisation in North-East Tanzania

African Health Sciences, 2021 • June 1, 2021

This study describes the occurrence of TSCI and prevailing complications during hospitalization in one rural area of Tanzania. The incidence of traumatic spinal cord injury in the Kilimanjaro region i...

KEY FINDING: The annual incidence rate of traumatic spinal cord injury in the Kilimanjaro region was found to be at least 38 cases per million population.

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