Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 71-80 of 702 results
Regenerative Therapy, 2023 • June 7, 2023
This meta-analysis evaluates the therapeutic potential of stem cells from human exfoliated deciduous teeth (SHED) in preclinical animal models across various diseases. The study found statistically si...
KEY FINDING: SHED intervention in several diseases depicted statistically significant therapeutic effects in periodontitis, pulpitis, spinal cord injury, parkinson's disease, alzheimer's disease, focal cerebral ischemia, peripheral nerve injury, and retinal pigmentosa.
Clin Spine Surg, 2024 • June 1, 2024
This meta-analysis compared surgical and conservative treatments for thoracolumbar fractures with a TLICS score of 4. The study found that surgical treatment may offer benefits in terms of faster retu...
KEY FINDING: Surgical treatment resulted in a shorter length of returning to work compared to nonsurgical treatment.
Neural Regeneration Research, 2023 • April 20, 2023
This study successfully established a novel mouse model of central cord syndrome (CCS) by applying controlled blunt trauma to the C6 spinal cord. Behavioral, histological, and MRI analyses confirmed t...
KEY FINDING: The mouse model of CCS exhibited impaired motor function in the front paws while retaining basic motor and sensory functions of the lower extremities, mirroring the symptoms of human CCS.
Neural Regeneration Research, 2023 • April 10, 2023
This case report details the management of a 23-year-old man with a penetrating cervical spinal cord injury from a wooden stick. The patient initially presented with tetraparesis but rapidly recovered...
KEY FINDING: Penetrating spinal cord injuries from wooden objects carry a high risk of infection.
Biomedicines, 2023 • July 7, 2023
This study developed an optimal sham configuration for transcutaneous tibial nerve stimulation (TTNS) to be used in randomized controlled trials (RCTs). The researchers tested three potential electrod...
KEY FINDING: The 5th metatarsal position with 3.2 cm electrodes was found to be the most suitable sham configuration, achieving a 100% motor response rate.
Indian Journal of Orthopaedics, 2023 • July 1, 2023
This case report describes a unique complication of Charcot Spinal Arthropathy (CSA) in a patient with a post-traumatic spinal cord injury, highlighting the replacement of vertebral structures with fi...
KEY FINDING: The patient exhibited exceptional spinal movement in the coronal and sagittal planes due to the replacement of the discal space and vertebral bodies with fibrotic tissue.
Medicine, 2023 • August 2, 2023
This meta-analysis aimed to determine the superior treatment method between surgical and conservative approaches for adult patients with Cervical Spinal Cord Injury Without Fracture and Dislocation (C...
KEY FINDING: Surgical treatment showed a significantly higher effective rate compared to conservative treatment (OR = 4.737, P < .001).
International Journal of Surgery Case Reports, 2023 • August 31, 2023
This case report describes a 65-year-old woman who developed difficult tracheostomy decannulation due to upper airway obstruction, which was attributed to nasogastric tube syndrome (NGTS). The patient...
KEY FINDING: The patient experienced severe inspiratory difficulty and supraglottic swelling, completely covering the opening of the glottis, when tracheostomy decannulation was attempted.
Neural Regen Res, 2024 • July 20, 2023
This systematic review analyzes 22 animal studies on distraction spinal cord injury (DSCI), focusing on neurophysiological, histological, and behavioral characteristics. The review identifies that the...
KEY FINDING: DSCI severity, assessed through neurophysiology, histology, and behavior, increases with the degree and duration of distraction, highlighting the importance of these factors in injury progression.
Korean J Pain, 2023 • August 1, 2023
This systematic review and meta-analysis evaluated the efficacy of muscimol in ameliorating nerve injury-related neuropathic pain based on preclinical studies. The study found that muscimol is effecti...
KEY FINDING: Muscimol significantly reduces mechanical allodynia (SMD = 1.78 [1.45–2.11]; P < 0.0001; I2 = 72.70%), mechanical hyperalgesia (SMD = 1.62 [1.28–1.96]; P < 0.0001; I2 = 40.66%), and thermal hyperalgesia (SMD = 2.59 [1.79–3.39]; P < 0.0001; I2 = 80.33%).