Browse the latest research summaries in the field of research methodology & design for spinal cord injury patients and caregivers.
Showing 221-230 of 702 results
BMJ Open, 2024 • January 1, 2024
The ChiRES study is designed as a prospective, multicentre cohort study to gather comprehensive data on Chinese patients with acute SCI. The study will collect detailed clinical data, blood samples, a...
KEY FINDING: The study aims to establish a multicentre database of clinical information and biospecimen samples of patients with acute SCI and to complete at least 1 year of follow-up.
South African Journal of Physiotherapy, 2024 • May 6, 2024
This scoping review aimed to identify and critically appraise existing clinical practice guidelines for chronic pain management in the spinal cord injury (SCI) population. The review found that most g...
KEY FINDING: One guideline met all the objectives of this scoping review.
Frontiers in Neurology, 2024 • May 9, 2024
This case report describes a 31-year-old man who developed isolated unilateral brachial plexus injury following acute carbon monoxide (CO) poisoning. The patient presented with weakness and sensory de...
KEY FINDING: A 31-year-old man developed left brachial plexopathy after CO poisoning, confirmed by electrophysiological studies showing severe abnormalities in the upper and moderate abnormalities in the middle branches.
BMJ Neurol Open, 2024 • May 20, 2024
This systematic review analysed 33 studies with 440 patients to understand spontaneous spinal cord infarction (SCInf). The review found that hypertension, smoking, dyslipidaemia, and diabetes were com...
KEY FINDING: Vascular risk factors, especially hypertension, play a significant role in spontaneous SCInf.
Nature Communications, 2024 • April 1, 2024
This article is an author's correction to a previously published study on intrathecal delivery of adipose-derived mesenchymal stem cells (AD-MSCs) in traumatic spinal cord injury. The correction invol...
KEY FINDING: The average duration between injury and AD-MSC injection was corrected to 12 months (range of 7–22).
Spinal Cord, 2024 • June 19, 2024
This study was a phase IIA clinical trial designed to assess the safety, tolerability, and preliminary efficacy of NFX88 in treating neuropathic pain in individuals with spinal cord injury. The trial ...
KEY FINDING: NFX88 treatment was found to be highly safe and well tolerated in individuals with spinal cord injury.
Life, 2024 • June 7, 2024
Electrophysiological studies, including EEG and EMG, are crucial for assessing brain and spinal cord function, neurodegeneration, and the effectiveness of therapies. These methods can be applied in bo...
KEY FINDING: EEG data in animals and humans are practically comparable under normal conditions, with some differences related to anatomical features and behavioral patterns.
Health Expectations, 2024 • June 19, 2024
This study aimed to develop key principles for PPI in preclinical spinal cord research to support researchers in conducting evidence‐informed PPI. Using a modified Delphi method, consensus was reached...
KEY FINDING: Consensus (> 75% agreement) was reached for a total of 27 principles, with 13 rated as essential and 14 rated as desirable.
BMC Medicine, 2024 • July 2, 2024
This investigation aggregates the latest data to assess the epidemiologic characteristics of SCI from 2000 to 2021. Based on limited data, this study found that although NTSCI incidence is lower than ...
KEY FINDING: The overall incidence rate of SCI was 23.77 per million people.
Scientific Reports, 2024 • June 24, 2024
This study introduces a nested ensemble algorithm to predict motor function recovery in TCSCI patients using early ASIA motor scores. The algorithm combines multiple machine learning models in two sta...
KEY FINDING: The nested ensemble algorithm achieved an accuracy of 80.6% and an F1 score of 80.6% in predicting motor function recovery after TCSCI.