Research Methodology & Design Research

KEY FINDING: The development of CPGs for SCI followed the methodology proposed by the Institute of Medicine, the Guideline International Network, and the GRADE Working Group.

KEY FINDING: Patients were 2 times more likely to recover by ≥2 grades on the ASIA Impairment Score (AIS) at 6 months and 12 months if they were decompressed within 24 hours compared to after 24 hours.

KEY FINDING: The USA, Canada, and Switzerland are the most prolific countries contributing to gait rehabilitation research in SCI.

KEY FINDING: Both self-report versions (SR-V1 and SR-V2) showed excellent intra-rater reliability and validity compared to the original face-to-face WISCI II.

KEY FINDING: The patient with complete C4 tetraplegia showed considerable neurological recovery after 6 months of MLC901 supplementation.

KEY FINDING: The patient, initially presenting with complete motor and sensory loss (ASIA score A), showed improvement to an MRC score of 3 after surgery and rehabilitation.

KEY FINDING: The subscales Selfcare and Mobility showed good fit to the Rasch model, indicating that they accurately measure independence in these areas.

KEY FINDING: We present a case of a 33-year-old bed ridden male, diagnosed with NHO involving all 4 limbs (bilateral hip, right knee, right shoulder, left elbow).

KEY FINDING: Environmental barriers, including poor accessibility and inadequate healthcare services, significantly impede community reintegration for individuals with SCI.

KEY FINDING: People affected by spinal cord injury desire further involvement in pre-clinical research through dialogue and contact with researchers.