Author Correction: Intrathecal delivery of adipose-derived mesenchymal stem cells in traumatic spinal cord injury: Phase I trial

Nature Communications, 2024 · DOI: https://doi.org/10.1038/s41467-024-48979-7 · Published: April 1, 2024

Spinal Cord Injury Regenerative Medicine Research Methodology & Design

Simple Explanation

This article is a correction to a previously published study on the use of adipose-derived mesenchymal stem cells (AD-MSCs) to treat traumatic spinal cord injuries. The correction addresses an error in the reported average duration between the spinal cord injury and the injection of AD-MSCs, changing it from 11 months to 12 months. A correction was also made to Table 1, specifically the time between injury and injection for Patient 1, changing it from 22 months to 11 months.

Study Duration

Not specified

Participants

10 patients with traumatic spinal cord injury

Evidence Level

Level I, Phase I Trial (Corrected Data)

Key Findings

1
The average duration between injury and AD-MSC injection was corrected to 12 months (range of 7–22).
2
The time between injury and injection for Patient 1 in Table 1 was corrected from 22 months to 11 months.
3
The corrected table provides accurate data for the time between injury and injection for each of the 10 patients enrolled in the study.

Research Summary

This article is an author's correction to a previously published study on intrathecal delivery of adipose-derived mesenchymal stem cells (AD-MSCs) in traumatic spinal cord injury. The correction involves a change in the reported average duration between injury and AD-MSC injection, as well as a correction to a specific data point in Table 1. The corrected information provides more accurate data regarding the timing of AD-MSC injection in relation to the initial spinal cord injury for the patients involved in the Phase I trial.

Practical Implications

Data Accuracy

Ensures the accuracy of published data, which is crucial for the integrity of scientific research.

Clinical Interpretation

Corrected timing data could influence the interpretation of the trial's outcomes and inform future research design.

Reproducibility

Accurate data is essential for the reproducibility and validation of the study's findings by other researchers.

Study Limitations

1
This is a correction, not new research; it addresses errors in previously published data.
2
The correction focuses on specific data points (average time and one patient's data) and doesn't alter the overall study design or conclusions.
3
The study itself (to which this is a correction) may have other limitations that are not addressed in this correction.

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