Pain Management Research

KEY FINDING: SNI enhanced the C component of eLFPs in bilateral cortexes elicited by stimulating the contralateral but not the ipsilateral lateral aspect of the hind paw.

KEY FINDING: The patient experienced transient improvements post-cervical decompression but later developed delirium, worsening right-sided weakness, and bilateral foot drop.

KEY FINDING: The patient experienced left-sided hemiparesis after IDET, indicating neurological damage. MRI confirmed cervical cord edema.

KEY FINDING: Targeted blockade of spinal α2 adrenoceptors can reduce spinal nociceptive transmission in vivo.

KEY FINDING: SNI led to the downregulation of Vof16 expression in spinal dorsal horn (SDH) of lumbar enlargement.

KEY FINDING: China and the United States are the leading countries in research on glial cells and neuropathic pain, with the University of California system being the top institution.

KEY FINDING: The combination of Shinbaro and celecoxib synergistically reduced mechanical hyperalgesia and paw edema in mice with CFA-induced inflammatory pain.

KEY FINDING: Daytime and nighttime pain levels (Visual Analog Scale) improved after botulinum toxin type A injection.

KEY FINDING: ACY-1215 ameliorated SNI-induced pain starting from Day 7 post-SNI operation, achieving relatively stable efficacy by Day 13 in both male and female mice.

KEY FINDING: EA treatment significantly alleviated pain hypersensitivity by increasing the MWT and PWL in CCI rats.