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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Oncology Research

Browse the latest research summaries in the field of oncology for spinal cord injury patients and caregivers.

Showing 91-100 of 200 results

Spinal Cord InjuryOncologyPublic Health

Colorectal cancer mortality after spinal cord injury

The Journal of Spinal Cord Medicine, 2022 • May 1, 2022

This study compared CRC mortality in SCI patients to CRC mortality in the general population to determine if any disparities exist. The study found no significant difference in overall CRC mortality b...

KEY FINDING: The overall standardized mortality ratio (SMR) for CRC mortality in the SCI population was 1.11 (95% CI [0.94, 1.31]), indicating no statistically significant increase compared to the general population.

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Spinal Cord InjuryUrologyOncology

Bladder management, severity of injury and period of latency: a descriptive study on 135 patients with spinal cord injury and bladder cancer

Spinal Cord, 2021 • June 17, 2021

This study, based on data from 135 SCI/D patients with bladder cancer, confirms that bladder cancer tends to occur at a younger age and with more advanced tumors in SCI/D patients. The study found no ...

KEY FINDING: No significant differences were found in tumor characteristics when stratified by bladder management, SCI/D severity, and ASIA classification.

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Spinal Cord InjuryOncologyRehabilitation

Survival, discharge destination, and referral for rehabilitation after metastatic spinal cord compression surgery

Spinal Cord Series and Cases, 2021 • July 15, 2021

This retrospective study investigated survival, rehabilitation needs, and discharge destinations of patients undergoing surgery for metastatic spinal cord compression (MSCC). The study revealed a disc...

KEY FINDING: The probability of survival after 90- and 180-days post-surgery were 78% and 57%, respectively.

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OncologyGenetics

CtBP modulates Snail-mediated tumor invasion in Drosophila

Cell Death Discovery, 2021 • May 14, 2021

This study investigates the role of CtBP and Snail in tumor invasion using Drosophila as a model organism. The researchers found that both CtBP and Snail are required for tumor growth and invasion tri...

KEY FINDING: Depletion of CtBP or Snail (Sna) suppressed RasV12/lgl-/--triggered tumor growth and invasion, and disrupted cell polarity-induced invasive cell migration in Drosophila.

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OncologyAgingNeurology

Confusion, cognitive impairment, and spinal cord compression caused by plasmacytoma: a case report

BMC Neurol, 2021 • June 29, 2021

This case report describes an 80-year-old man who presented to the ER with confusion and walking difficulties and was found to have spinal cord compression caused by a plasmacytoma. The patient's CSF ...

KEY FINDING: Spinal cord compression by plasmacytoma can lead to abnormal CSF levels of several known pathology markers for Alzheimer’s disease and neuronal damage.

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OncologyResearch Methodology & Design

Recent advances and new discoveries in the pipeline of the treatment of primary spinal tumors and spinal metastases: a scoping review of registered clinical studies from 2000 to 2020

Neuro-Oncology, 2022 • January 1, 2022

This scoping review highlights the key features of 174 clinical studies on spinal neoplasms registered from 2000 to 2020. Clinical trials are more focused on metastatic tumors than primary tumors, ref...

KEY FINDING: Most registered clinical studies were interventional and led by single institutions, mainly in North America and Europe.

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OncologyNeurologyRehabilitation

Primary Melanocytomas of the Spinal Cord: Case Studies and Rehabilitation Perspectives

Archives of Rehabilitation Research and Clinical Translation, 2021 • January 1, 2021

This case series highlights the importance of the rehabilitation team in the continuum of care for patients undergoing resection of primary melanocytomas of the spinal cord. Presenting symptoms can be...

KEY FINDING: Primary spinal melanocytomas, though rare, may be more common than reported due to their insidious nature and non-specific symptoms, potentially leading to delayed or missed diagnoses.

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OncologySurgery

Effect of Minimally Invasive Spine Stabilization in Metastatic Spinal Tumors

Medicina, 2022 • March 1, 2022

This study evaluated the effect of minimally invasive spine stabilization (MISt) in 51 patients with metastatic spinal tumors. MISt is a minimally invasive fixation procedure that temporarily stabilize...

KEY FINDING: MISt can benefit patients who are ineligible for conventional, highly invasive surgery.

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OncologySurgery

A Stepwise Posterolateral Approach for Computed Tomography Guided C2 (Axis) Transpedicular Biopsy: A Technical Note

Journal of Orthopaedic Case Reports, 2021 • September 1, 2021

This case report presents a case of adenocarcinoma diagnosed with CT-guided percutaneous biopsy of the C2 body using a posterolateral approach under local anesthesia. Stepwise approach for CT-guided m...

KEY FINDING: The study demonstrates that a minimally invasive posterolateral percutaneous CT-guided approach for C2 biopsy is safe and precise.

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OncologyDisabilityPublic Health

Cancer Disparities Experienced by People with Disabilities

Int. J. Environ. Res. Public Health, 2022 • July 27, 2022

People with disabilities, a growing and disadvantaged group, face persistent barriers to healthcare and have a high prevalence of chronic health conditions. They experience cancer health disparities d...

KEY FINDING: People with disabilities report disproportionately higher rates of risk factors, including obesity, cigarette smoking, and substance misuse.

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