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  4. Reevaluating age restrictions of spinal metastasis surgery in elderly groups with over 2‑year follow‑up

Reevaluating age restrictions of spinal metastasis surgery in elderly groups with over 2‑year follow‑up

Neurosurgical Review, 2023 · DOI: https://doi.org/10.1007/s10143-023-02217-8 · Published: November 21, 2023

OncologySurgery

Simple Explanation

This study investigates surgical outcomes for elderly patients with spinal metastasis focusing on those aged 65-79 and those 80+. It seeks to understand if age should limit surgical intervention. The study looks at patient data over a 16-year period, considering factors like age, comorbidities, and surgical outcomes to evaluate the benefits and risks of laminectomy in older patients. The findings suggest that age alone should not prevent necessary spine surgery, as surgery can improve functionality, though older patients may experience reduced survival times.

Study Duration
September 2005 and December 2020
Participants
99 patients (65 patients aged 65–79 years and 34 patients aged 80 years and older) diagnosed with MESCC
Evidence Level
Retrospective review

Key Findings

  • 1
    Octogenarians had significantly higher age-adjusted Charlson Comorbidity Index (CCI) scores compared to the 65–79 age group, indicating a greater burden of comorbidities.
  • 2
    The older group demonstrated more pronounced neurological and functional decline, evidenced by lower Karnofsky Performance Index (KPI) scores.
  • 3
    Despite shorter decompression duration, the older group had more spinal levels needing decompression and experienced greater blood loss during surgery.

Research Summary

This study compares surgical outcomes in elderly patients (65–79 years vs. ≥ 80 years) undergoing laminectomy for spinal metastasis with epidural spinal cord compression (MESCC). The research found that while octogenarians had higher comorbidity rates and poorer functional status, surgery still led to improvements in both age groups, though younger patients recovered more quickly. The study concludes that age alone should not be a contraindication for spine surgery in MESCC patients, as timely intervention can improve quality of life, even with potentially shortened survival rates.

Practical Implications

Informed Decision Making

Age should not be the sole determinant when considering spine surgery for MESCC; a patient's overall health and functional status should be prioritized.

Improved Patient Management

Enhance education for practitioners to expedite patient management, reduce delays, and ensure prompt multidisciplinary consultations for MSCC.

Surgical Intervention Benefits

Surgical interventions can significantly improve patient functionality while maintaining acceptable complication rates, especially with timely diagnosis and treatment.

Study Limitations

  • 1
    Modest patient cohort limiting the scope of conclusions.
  • 2
    Lack of a younger control group for comparison.
  • 3
    Potential for selection bias due to the retrospective design.

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