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  4. Evaluation of computed tomography artefacts of carbon-fiber and titanium implants in patients with spinal oligometastatic disease undergoing stereotactic ablative radiotherapy

Evaluation of computed tomography artefacts of carbon-fiber and titanium implants in patients with spinal oligometastatic disease undergoing stereotactic ablative radiotherapy

Scientific Reports, 2024 · DOI: 10.1038/s41598-024-52498-2 · Published: January 19, 2024

OncologyMedical Imaging

Simple Explanation

This study evaluated artefacts on computed tomography (CT) images using Hounsfield units (HU) in patients with spinal oligometastatic disease who received carbon-fiber (CF; n = 11) or titanium (n = 11) spine implants and underwent stereotactic ablative radiotherapy (SABR). Significant differences in HU were observed at the vertebral body, the pedicle, and the spinal cord at the lowest instrumented vertebra level for both CF and titanium (average increase 1.54-fold and 5.11-fold respectively). The relatively high postoperative HU-increase after insertion of titanium implants indicated CT artefacts, while the relatively low HU-increase of CF implants was not associated with artefacts.

Study Duration
2018 and 2020
Participants
22 patients with spinal oligometastatic disease
Evidence Level
Not specified

Key Findings

  • 1
    Significant increases in Hounsfield units (HU) were observed at the vertebral body, pedicle, and spinal cord at the lowest instrumented vertebra level for both carbon-fiber (CF) and titanium implants.
  • 2
    At the metastatic spinal cord compression level, a trend towards a higher HU-increase was observed in titanium implants compared with CF implants.
  • 3
    A CT artefact grading system based on postoperative HU-increase is proposed, which provides information on the ability to assess anatomically relevant structures.

Research Summary

This study utilized a quantitative technique to compare pre- and postoperative CT artifacts produced by CF and titanium implants in patients with spinal oligometastatic disease (OMD) undergoing stereotactic ablative radiotherapy (SABR). A greater increase in Hounsfield units (HU) was observed in the group treated with titanium spine implants than in the group treated with CF spine implants. Therefore, we propose a CT artefact grading system based on postoperative HU-increase. This could be used in future studies to assess if less CT artefacts due to treatment with CF implants lead to time savings during radiotherapy treatment planning

Practical Implications

Reduced CT Artifacts

Carbon-fiber implants could lead to reduced CT artifacts compared to titanium implants, potentially facilitating easier contouring in radiotherapy planning.

Improved Radiotherapy Planning

Less CT artifacts may result in time savings during radiotherapy treatment planning, leading to more efficient workflows.

Enhanced Tumor Control

The reduction in CT artifacts from carbon-fiber implants may lead to better tumoricidal effects and decreased adverse effects, particularly with particle therapy.

Study Limitations

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