Immunology Research

KEY FINDING: Ethyl pyruvate (EP) inhibits the expression of various inflammatory mediators and eliminates the release of oxidative stress factors, thus exerting potent anti-inflammatory roles.

KEY FINDING: High TRIM28 expression level was associated with T classification, pathologic stage, histologic grade, and serum AFP levels.

KEY FINDING: The xanthohumol-loaded PLGA scaffolds exhibited anti-inflammatory properties in vitro, reducing the expression of inflammatory cytokines (IL-1β and TNF-α) in macrophages.

KEY FINDING: There is a significant correlation between semi-quantitative SARS-CoV-2 IgG ratio values and in vitro antibody functionality.

KEY FINDING: DOCK2 regulates immunosuppressive function in human stromal cell models.

KEY FINDING: Two podhfr mutations, S58R and S113N/T, were detected in P. ovale curtisi with high/moderate frequencies.

KEY FINDING: CXCL10, a chemokine, is significantly upregulated following SCI and plays a crucial role in the development of neuroinflammation.

KEY FINDING: M1 macrophages/microglia exacerbate inflammation and tissue damage after SCI by releasing pro-inflammatory cytokines, while M2 macrophages/microglia promote tissue repair and reduce inflammation by releasing anti-inflammatory cytokines.

KEY FINDING: Escherichia coli was the most frequently identified bacterial species in positive urine cultures, representing 42.7% of cases.

KEY FINDING: Glial cells in the spinal cord, like astrocytes and microglia, are not just supportive cells but also key players in the immune response after SCI, influencing inflammation and tissue repair.