Browse the latest research summaries in the field of immunology for spinal cord injury patients and caregivers.
Showing 311-320 of 730 results
European Journal of Trauma and Emergency Surgery, 2022 • June 3, 2022
This study compared patients with pyogenic spinal infections with and without spinal cord injury (SCI), analyzing diagnostics, therapy, and outcomes. The study found that while overall survival was si...
KEY FINDING: The presence of endocarditis was significantly higher in the noSCI group compared to the SCI group (9% vs. 0%; p=0.03).
Med, 2022 • August 12, 2022
This study investigated the impact of heterologous prime-boost COVID-19 vaccination schedules on antibody response against SARS-CoV-2 variants in healthcare workers. The researchers found that the ord...
KEY FINDING: Strongest serum neutralization activity against the SARS-CoV-2 variant B.1.617.2 among recipients of heterologous BBIBP-CorV/CoronaVac and WIBP-CorV/CoronaVac.
Journal of Neuroinflammation, 2022 • June 5, 2022
This study investigates the role of Apelin in treating spinal cord injury (SCI) by reducing neuroinflammation and promoting neural stem cell (NSC) proliferation and differentiation. The researchers fo...
KEY FINDING: Apelin expression decreases after SCI and then increases later, suggesting its involvement in both injury and repair.
Frontiers in Immunology, 2022 • June 28, 2022
This study performed a detailed immune profiling of SCI patients in the (sub)acute and chronic disease phase using high-dimensional flow cytometry. Changes in the frequencies of circulating immune cel...
KEY FINDING: Total and CD4+ T cell frequencies were increased in cSCI patients.
The Journal of Spinal Cord Medicine, 2020 • May 1, 2020
The study prospectively evaluated urodynamic changes in individuals with SCI practicing CIC to understand long-term complications despite CIC and compare the urodynamic bladder profile of overactive d...
KEY FINDING: Cystometric capacity and compliance decreased significantly over time, despite regular CIC and antimuscarinic medication use.
JOURNAL OF NEUROTRAUMA, 2019 • December 15, 2019
The study assessed factors associated with circulating BAFF in non-ambulatory males with chronic SCI, finding that active smokers had significantly greater BAFF levels than former/nonsmokers. The rese...
KEY FINDING: Active smokers had significantly greater BAFF levels than former/nonsmokers (871 pg/mL vs. 665 pg/ml, p = 0.002).
JOURNAL OF NEUROTRAUMA, 2020 • February 1, 2020
This study investigates the overexpression of TMEM176A and TMEM176B genes in circulating monocytes of individuals with chronic SCI, suggesting their potential role in suppressing dendritic cell functi...
KEY FINDING: TMEM176A and TMEM176B are significantly elevated in circulating monocytes from subjects with chronic SCI.
The Journal of Spinal Cord Medicine, 2019 • January 1, 2019
The study aimed to develop quality indicators for urinary tract infection (UTI) management in spinal cord injury (SCI/D) rehabilitation to reduce inappropriate antibiotic use. A combination of evidenc...
KEY FINDING: A structure indicator was defined as the proportion of patients able to follow-up regarding urine culture results within 48-72 hours of collection.
Spinal Cord Series and Cases, 2019 • September 1, 2019
This case report presents the successful management of chronic prostatitis in a spinal cord injury (SCI) male through transurethral prostatectomy (TURP) after conservative treatments failed. The patie...
KEY FINDING: The patient, a 52-year-old male with T12 AIS A SCI, experienced resolution of recurrent UTIs and urethral discharge after undergoing TURP.
The Journal of Spinal Cord Medicine, 2020 • January 1, 2020
This retrospective cohort study examined the incidence and risk factors for healthcare facility-onset, healthcare facility-associated (HO-HCFA) Clostridioides difficile infection (CDI) in Veterans wit...
KEY FINDING: Antibiotic and PPI/H2 blocker use were independently associated with HO-HCFA CDI.