Immunology Research

KEY FINDING: The severity of spinal cord compression correlated with the proportion of activated microglia and hematogenous macrophages in the spinal cord.

KEY FINDING: Sepsis survivors exhibit chronic muscle weakness for at least one month, even after muscle mass recovery.

KEY FINDING: Surveillance of CAUTI is challenging in the SCI population because the ability to detect symptoms typically used to diagnose CAUTI, such as suprapubic pain and dysuria, is often impaired.

KEY FINDING: Downregulation of α-synuclein reduces inflammatory infiltration and preserves myelin after SCI.

KEY FINDING: Awareness of diagnostic CDC-criteria for pneumonia was confirmed by 88% of departments.

KEY FINDING: CX3CR1 and CX3CL1 expression levels increase after spinal cord injury, peaking at 10 days, suggesting their involvement in the inflammatory response.

KEY FINDING: Nerve injury can hasten functional decline and shorten survival in SOD1 rat models of ALS, suggesting injury can initiate earlier disease onset and promote local spread.

KEY FINDING: SCI patients are at a significantly higher risk for developing dementia, with some studies suggesting they are 13 times more likely to develop cognitive impairments.

KEY FINDING: C1q activates specific intracellular signaling pathways in NSC to modulate NSC behavior.

KEY FINDING: The study aims to evaluate the ability of parameters of respiratory function to predict and understand variation in inpatient risk of pneumonia in SCI.