Cureus, 2023 · DOI: 10.7759/cureus.37168 · Published: April 5, 2023
West Nile encephalitis, a rare complication of West Nile virus (WNv) infection, can present with symptoms mimicking other neurological diseases. This article reports a case of a 60-year-old female who developed bilateral upper extremity tremors with West Nile encephalitis. The patient presented with high fevers and new onset confusion, followed by persistent tremors throughout her hospitalization. Brain imaging showed no abnormalities, but cerebral spinal fluid (CSF) was positive for WNv IgM, confirming the diagnosis. When patients present with movement disorders and confusion, it often suggests brain or spinal cord injury or other neurological illnesses. However, viral etiologies should be considered, especially when fever and elevated white blood cell count are present.
Clinicians should consider West Nile virus infection in patients presenting with tremors, fever, and confusion, especially during outbreaks.
Focus on supportive care, as there is no specific antiviral treatment for West Nile virus, but early diagnosis can prevent unnecessary antibiotic or antiviral use for other conditions.
Patients with West Nile encephalitis may benefit from occupational and physical therapy to improve functional status and manage persistent tremors.