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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Gastroenterology Research

Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.

Showing 61-70 of 136 results

Spinal Cord InjuryGastroenterologyResearch Methodology & Design

Creation and validation of a new tool for the monitoring efficacy of neurogenic bowel dysfunction treatment on response: the MENTOR tool

Spinal Cord, 2020 • January 27, 2020

This study introduces and validates the MENTOR tool, designed to monitor the effectiveness of neurogenic bowel dysfunction (NBD) treatment in individuals with spinal cord injury (SCI). The MENTOR tool...

KEY FINDING: The MENTOR tool shows good agreement with expert clinicians in identifying patients who need a change in bowel management.

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Spinal Cord InjuryUrologyGastroenterology

Recommendations for evaluation of neurogenic bladder and bowel dysfunction after spinal cord injury and/or disease

The Journal of Spinal Cord Medicine, 2020 • January 1, 2020

This article provides readers with recommendations for clinical and diagnostic tools and measures including SRMs and datasets currently available for use. We describe measurement properties, suggested...

KEY FINDING: The study identified 15 clinical assessment modalities for neurogenic bladder and 12 for neurogenic bowel in SCI/D.

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Spinal Cord InjuryUrologyGastroenterology

Neurogenic bowel and bladder evaluation strategies in spinal cord injury: New directions

The Journal of Spinal Cord Medicine, 2020 • January 1, 2020

Spinal cord injury is associated with comorbidities that can limit functional independence, mobility and socialization, including neurogenic bowel and bladder. In March 2017, the Craig H. Neilsen Foun...

KEY FINDING: Holmes et al. identify and distinguish outcome metrics as fundamental, recommended, supplemental, exploratory, or not recommended in preclinical SCI research.

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NeurologyPain ManagementGastroenterology

Treatment of Chronic Abdominal Pain With 10-kHz Spinal Cord Stimulation: Safety and Efficacy Results From a 12-Month Prospective, Multicenter, Feasibility Study

Clinical and Translational Gastroenterology, 2020 • February 7, 2020

This prospective, single-arm study was designed to evaluate the safety and efficacy of 10-kHz spinal cord stimulation (SCS) in patients with intractable CAP over a 12-month follow-up period. After 12 ...

KEY FINDING: After 12 months of treatment with 10-kHz SCS, 78.3% of subjects were responders (pain relief of ‡50%).

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Spinal Cord InjuryGastroenterologyNutrition & Dietetics

Diet in neurogenic bowel management: A viewpoint on spinal cord injury

World Journal of Gastroenterology, 2020 • May 28, 2020

This review provides dietary advice for individuals with spinal cord injury (SCI) and neurogenic bowel dysfunction (NBD), considering associated health conditions and the impact of lifestyle. It sugge...

KEY FINDING: Individuals with SCI have lower fiber intake and greater energy intake relative to energy needs compared to guidelines for the general population.

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Spinal Cord InjuryGastroenterologyResearch Methodology & Design

Colonic obstruction in a tetraplegic patient: a common symptom from an uncommon cause

Spinal Cord Series and Cases, 2020 • June 17, 2020

This case report highlights the difficulty in diagnosing acute abdominal conditions in patients with spinal cord injuries (SCI) due to altered sensation and multiple co-morbidities. A 57-year-old tetr...

KEY FINDING: The patient presented with nausea, vomiting, abdominal distension, and feeding intolerance, initially leading to a diagnosis of pseudo-gut obstruction due to severe hyponatremia.

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Spinal Cord InjuryNeurologyGastroenterology

Effects of sacral nerve electrical stimulation on 5‑HT and 5‑HT3AR/5‑HT4R levels in the colon and sacral cord of acute spinal cord injury rat models

Molecular Medicine Reports, 2020 • January 1, 2020

This study investigated the effects of sacral nerve electrical stimulation (SNS) on defecation function and serotonin (5-HT) levels in a rat model of acute severe spinal cord injury (SCI). The results...

KEY FINDING: SNS significantly increased the quantity of feces, shortened the time to the first fecal passage, and improved fecal texture and colon histology in SCI rats.

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Spinal Cord InjurySurgeryGastroenterology

“Imola-Montecatone” subtotal colectomy to improve bowel management in spinal cord injury patients. Retrospective analysis in 19 cases

Spinal Cord Series and Cases, 2020 • June 26, 2020

This retrospective study evaluated the effectiveness of the 'Imola-Montecatone' subtotal colectomy technique in improving bowel management for SCI patients with neurogenic bowel dysfunction. The proce...

KEY FINDING: The study of 19 individuals undergoing the 'Imola-Montecatone' procedure reported no major complications after one year of follow-up.

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Spinal Cord InjuryGastroenterology

Alterations in the fecal microbiota of patients with spinal cord injury

PLOS ONE, 2020 • August 4, 2020

This study investigated the fecal microbiome composition in patients with spinal cord injury (SCI) compared to healthy controls, revealing significant differences in the structure and quantity of feca...

KEY FINDING: The structure and quantity of fecal microbiota differed significantly between patients with SCI and healthy controls.

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Spinal Cord InjuryUrologyGastroenterology

Needs, priorities, and attitudes of individuals with spinal cord injury toward nerve stimulation devices for bladder and bowel function: A survey

Spinal Cord, 2020 • November 1, 2020

This study aimed to understand the needs and priorities of individuals with SCI regarding bladder and bowel management and their willingness to use neuromodulation interventions. The survey results in...

KEY FINDING: Bladder emptying without catheters was the top priority for restoring bladder function for those surveyed.

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