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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Gastroenterology Research

Browse the latest research summaries in the field of gastroenterology for spinal cord injury patients and caregivers.

Showing 71-80 of 136 results

Spinal Cord InjuryGastroenterologyRehabilitation

Effects of Lower Thoracic Spinal Cord Stimulation on Bowel Management in Individuals with Spinal Cord Injury

Arch Phys Med Rehabil, 2021 • June 1, 2021

This pilot study investigated the effects of spinal cord stimulation (SCS) on bowel management (BM) in individuals with cervical spinal cord injury (SCI). The study found that SCS significantly reduce...

KEY FINDING: SCS significantly reduced the time required for BM routines from 118±34 minutes to 18±2 minutes (p<0.05).

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Spinal Cord InjuryHealthcareGastroenterology

A Primary Care Provider’s Guide to Neurogenic Bowel Dysfunction in Spinal Cord Injury

Top Spinal Cord Inj Rehabil, 2020 • July 1, 2020

SCI may significantly impact the gastrointestinal (GI) tract, causing dysmotility and sphincter dysfunction that may diminish the quality of life (QOL) and opportunities for social integration for ind...

KEY FINDING: People with SCI consistently rank neurogenic bowel dysfunction (NBD) as an important health concern.

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Alternative MedicineNeurologyGastroenterology

Electroacupuncture at Zusanli (ST36) Repairs Interstitial Cells of Cajal and Upregulates c-Kit Expression in Rats with SCI-Induced Neurogenic Bowel Dysfunction

Evidence-Based Complementary and Alternative Medicine, 2020 • November 27, 2020

This study aimed to explore the mechanisms of EA therapy on defecation dysfunction after SCI, focusing on the effect of EA on ICCs and c-Kit expression. The research found that EA at Zusanli (ST36) co...

KEY FINDING: Spinal cord injury resulted in abnormal morphology of interstitial cells of Cajal (ICCs) in the colon tissues of rats.

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Spinal Cord InjuryNursingGastroenterology

Quantitative assessment-based nursing intervention improves bowel function in patients with neurogenic bowel dysfunction after spinal cord injury: Study protocol for a randomized controlled study

Medicine, 2020 • December 18, 2020

This study investigates the effectiveness of a quantitative assessment-based nursing intervention for patients with neurogenic bowel dysfunction following spinal cord injury. The intervention aims to ...

KEY FINDING: The primary outcomes measured will be bowel function recovery and patient satisfaction. Secondary outcomes will include quality of life, assessed using the SF-36 questionnaire, which covers aspects like physical pain and mental health.

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NeurologyGastroenterologyRehabilitation

An open prospective study on the efficacy of Navina Smart, an electronic system for transanal irrigation, in neurogenic bowel dysfunction

PLoS ONE, 2021 • January 29, 2021

This open, prospective study evaluated the short-term efficacy and safety of the Navina Smart electronic TAI system in individuals with NBD secondary to SCI. Eighty-nine participants, TAI treatment-na...

KEY FINDING: The study found a significant decrease in the mean NBD score after three months of using Navina Smart, indicating improved bowel function.

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Spinal Cord InjuryParticipationGastroenterology

Spinal cord injuries and bowel stomas: timing and satisfaction with stoma formation and alterations in quality of life

Spinal Cord Series and Cases, 2021 • January 1, 2021

This cross-sectional study explored the satisfaction and quality of life (QOL) changes in individuals with spinal cord injury (SCI) who have undergone bowel stoma formation. The study found that the m...

KEY FINDING: Most participants with SCI were satisfied with their bowel stomas (96%).

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Spinal Cord InjuryNeurologyGastroenterology

Pharmacological Management of Neurogenic Bowel Dysfunction after Spinal Cord Injury and Multiple Sclerosis: A Systematic Review and Clinical Implications

J. Clin. Med., 2021 • February 22, 2021

This study systematically examined the current literature on pharmacological agents to manage neurogenic bowel dysfunction of individuals specifically with SCI or MS. The review included twenty-eight ...

KEY FINDING: There was a small amount of literature in SCI, there was little to no literature available for MS.

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Spinal Cord InjuryImmunologyGastroenterology

Effect of fecal microbiota transplantation on neurological restoration in a spinal cord injury mouse model: involvement of brain-gut axis

Microbiome, 2021 • March 17, 2021

This study investigated the effect of fecal microbiota transplantation (FMT) on neurological restoration in a spinal cord injury (SCI) mouse model. The results demonstrated that FMT facilitated functi...

KEY FINDING: Fecal microbiota transplantation (FMT) improved locomotor recovery in SCI mice, as indicated by increased BMS scores and improved gait parameters.

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Spinal Cord InjuryPharmacologyGastroenterology

The Addition of Transdermal Delivery of Neostigmine and Glycopyrrolate by Iontophoresis to Thrice Weekly Bowel Care in Persons with Spinal Cord Injury: A Pilot Study

Journal of Clinical Medicine, 2021 • March 8, 2021

This pilot study investigated the efficacy and safety of adding transdermal neostigmine and glycopyrrolate, delivered via iontophoresis, to the standard bowel care (SOC) regimen for individuals with s...

KEY FINDING: The addition of transdermal neostigmine and glycopyrrolate significantly reduced the time to bowel evacuation compared to standard of care alone.

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Spinal Cord InjuryAssistive TechnologyGastroenterology

The Effect of Exoskeletal-Assisted Walking on Spinal Cord Injury Bowel Function: Results from a Randomized Trial and Comparison to Other Physical Interventions

Journal of Clinical Medicine, 2021 • March 2, 2021

This study evaluated the impact of exoskeletal-assisted walking (EAW) on bowel function in individuals with spinal cord injury (SCI) compared to usual activity (UA). The study found some improvements ...

KEY FINDING: EAW reduced the amount of time needed for the bowel program in 24% of the participants.

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