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Making Spinal Cord Injury (SCI) Research Accessible to Everyone. Simplified summaries of the latest research, designed for patients, caregivers and anybody who's interested.

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Endocrinology Research

Browse the latest research summaries in the field of endocrinology for spinal cord injury patients and caregivers.

Showing 51-60 of 217 results

Spinal Cord InjuryEndocrinologyMusculoskeletal Medicine

A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury

Cell Reports Medicine, 2024 • December 17, 2024

This study investigates why severe injury to the central nervous system (CNS) triggers the development of large neurogenic heterotopic ossifications (NHOs) within periarticular muscles. The central rol...

KEY FINDING: Severe SCI causes a spike in blood corticosterone in mice, which is causal for NHO development.

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EndocrinologyOrthopedicsRehabilitation

Osteoporosis Knowledge and Awareness Among Patients and Accompanying Attendants: A Cross-Sectional Study in a Physical Medicine and Rehabilitation Department

Cureus, 2024 • December 17, 2024

This cross-sectional study assessed osteoporosis knowledge among 300 patients and attendants at a Physical Medicine and Rehabilitation department using the OKAT-H questionnaire. The study revealed a s...

KEY FINDING: The mean OKAT-H score was found to be 9.82 out of 20 (49.1%) with a standard deviation of 5.06.

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PharmacologyEndocrinologySurgery

GLP-1 Receptor Agonists: Beyond Diabetes—What the Neurosurgeon Needs to Know

Neurosurgery Practice, 2024 • June 27, 2024

This article reviews what neurosurgeons need to know about the perioperative management of GLP-1 RAs. It discusses existing literature in clinical and preclinical studies for potential indications and...

KEY FINDING: GLP-1 RAs require tailored management for surgical patients, according to recent guidance from the American Society of Anesthesiologists.

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Spinal Cord InjuryEndocrinologyNeurology

Low-dose testosterone replacement therapy and electrically evoked resistance training enhance muscle quality after spinal cord injury

Neural Regeneration Research, 2021 • August 1, 2021

This paper highlights the significance of adding low-dose testosterone replacement therapy (TRT) to electrically evoked resistance training (RT) for SCI patients. It addresses muscle hypertrophy and p...

KEY FINDING: The TRT + RT group displayed 30–34% increases in muscle cross sectional area (CSA) of the knee extensors with no significant change observed in the TRT group.

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Spinal Cord InjuryPharmacologyEndocrinology

Treatment of obesity in spinal cord injury with tirzepatide: a case report

Spinal Cord Series and Cases, 2025 • February 21, 2025

Individuals with SCI experience alterations in metabolism that result in increased central obesity, insulin resistance, and dyslipidemia placing them at elevated risk for developing cardiometabolic di...

KEY FINDING: The patient lost 31 pounds after 3 months of tirzepatide treatment and saw improvements in his lipid profile.

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EndocrinologyRehabilitation

A Home‐Based Behaviour Change Intervention With Sedentary Behaviour and Physical Activity in People With Stroke and Diabetes—A Feasibility and Safety Study

Physiotherapy Research International, 2025 • January 1, 2025

This study aimed to determine the feasibility and safety of the ELiR intervention in stroke survivors with DM targeting SB and PA through motivational interviewing. Overall, the intervention was feasi...

KEY FINDING: The ELiR intervention showed high adherence among participants.

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UrologyEndocrinologyWomen's Health

Recent Advances in the Diagnosis and Management of Retrograde Ejaculation: A Narrative Review

Diagnostics, 2025 • March 14, 2025

Retrograde ejaculation (RE) is a condition where the forward expulsion of seminal fluid is impaired, leading to infertility and psychological distress in affected individuals. Management strategies for...

KEY FINDING: Diagnosis of RE relies on patient history, lab analysis of post-ejaculatory urine samples, and advanced imaging.

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Spinal Cord InjuryEndocrinologyNeurology

Electrically induced cycling and nutritional counseling for counteracting obesity after spinal cord injury: A pilot study

The Journal of Spinal Cord Medicine, 2021 • July 1, 2021

This pilot study investigated the efficacy of combining interval functional electrical stimulation (FES) cycling with nutritional counseling in obese adults with SCI. The FES & Nutri group showed a st...

KEY FINDING: Participants in the FES & Nutri group had a statistically significant greater decrease in body fat percentage compared to those in the Nutri Only group.

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Spinal Cord InjuryEndocrinologyRehabilitation

Rehabilitation interventions to modify endocrine-metabolic disease risk in individuals with chronic spinal cord injury living in the community (RIISC): A systematic search and review of prospective cohort and case–control studies

The Journal of Spinal Cord Medicine, 2023 • January 1, 2023

This review examined studies on how rehabilitation affects endocrine-metabolic disease (EMD) outcomes in people with chronic spinal cord injuries (SCI). The review found some evidence that exercises u...

KEY FINDING: Electrical stimulation-assisted training showed statistically significant effects on lower-extremity bone outcomes.

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Spinal Cord InjuryEndocrinologyPhysiology

Body composition and metabolic parameters in men with chronic traumatic paraplegia – A pilot study from India

The Journal of Spinal Cord Medicine, 2022 • January 1, 2022

This study compared body composition and metabolic profiles of men with paraplegia to able-bodied men, finding that those with paraplegia had lower lean mass and higher fat mass despite similar BMIs. ...

KEY FINDING: Men with paraplegia have significantly lower lean mass index (LMI) and appendicular lean mass index (ALMI) compared to able-bodied controls.

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